Description

  • Product name

    Human APXL peptide
  • Animal free

    No
  • Nature

    Synthetic
    • Species

      Human
    • Sequence

      KCLLDSLQPERGK
    • Amino acids

      1604 to 1616

Specifications

Our Abpromise guarantee covers the use of ab23127 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Reconstitution
    Reconstitute to 1mg/ml with water. (Lyophilised from water.)

General Info

  • Alternative names

    • 4832440C16
    • Ab2-404
    • Apical like protein
    • Apical like protein APXL protein
    • apical protein of Xenopus-like
    • Apical protein Xenopus laevis like
    • apical protein, Xenopus laevis-like
    • apical protein-like
    • apical protein-like (Xenopus laevis)
    • Apical-like protein
    • APX homolog of Xenopus
    • C630003H05Rik
    • DKFZp781J074
    • FLJ39277
    • HSAPXL
    • Liver regeneration-related protein LRRG167
    • OTTHUMP00000022887
    • Protein Apxl
    • Protein Shroom2
    • Shrm2
    • SHRM2_HUMAN
    • SHROOM 2
    • Shroom family member 2
    • shroom2
    see all
  • Function

    May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution.
  • Tissue specificity

    Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas.
  • Sequence similarities

    Belongs to the shroom family.
    Contains 1 ASD1 domain.
    Contains 1 ASD2 domain.
    Contains 1 PDZ (DHR) domain.
  • Domain

    The ASD1 domain mediates F-actin binding.
  • Cellular localization

    Apical cell membrane. Cell junction > tight junction. Cytoplasm > cytoskeleton. Associates with cortical F-actin.
  • Information by UniProt

References

ab23127 has not yet been referenced specifically in any publications.

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