Description

Associated products

Specifications

Our Abpromise guarantee covers the use of ab241272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

General Info

  • Alternative names

    • AQP 1
    • AQP CHIP
    • AQP-1
    • AQP1
    • AQP1_HUMAN
    • aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group)
    • aquaporin 1 (Colton blood group)
    • Aquaporin CHIP
    • Aquaporin-1
    • Aquaporin-CHIP
    • Aquaporin1
    • Channel forming integral protein 28kDa
    • Channel like integral membrane protein 28 kDa
    • CHIP 28
    • CHIP28
    • CO
    • Colton blood group
    • Growth factor induced delayed early response protein
    • MGC26324
    • Urine water channel
    • Water channel protein CHIP 29
    • Water channel protein CHIP29
    • Water channel protein for red blood cells and kidney proximal tubule
    see all
  • Function

    Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
  • Tissue specificity

    Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.
  • Sequence similarities

    Belongs to the MIP/aquaporin (TC 1.A.8) family.
  • Domain

    Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
  • Cellular localization

    Membrane.
  • Information by UniProt

References

ab241272 has not yet been referenced specifically in any publications.

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