Product nameHuman ARAP1 peptide
See all ARAP1 proteins and peptides
Amino Acid Sequence
Amino acids1198 to 1210
Our Abpromise guarantee covers the use of ab23119 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-ARAP1 antibody (ab5912)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- ANK repeat and PH domain-containing protein 1
- ARAP 1
FunctionPhosphatidylinositol-3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol-3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5.
Tissue specificityDetected in heart, skeletal muscle, spleen, kidney, liver, placenta, lung, peripheral blood leukocytes, adrenal gland, bone marrow, brain, lymph node, mammary gland, prostate, spinal cord, stomach, thyroid and trachea.
Sequence similaritiesContains 1 Arf-GAP domain.
Contains 4 PH domains.
Contains 1 Ras-associating domain.
Contains 1 Rho-GAP domain.
Contains 1 SAM (sterile alpha motif) domain.
Cellular localizationCytoplasm. Golgi apparatus > Golgi stack membrane. Cell membrane. Associated with Golgi stacks in resting cells. Throughout the cytoplasm and in surface protrusion in cells that are in the process of attaching to a surface and spreading.
- Information by UniProt
ab23119 has not yet been referenced specifically in any publications.