Product nameHuman BCAR3 peptide
See all BCAR3 proteins and peptides
Amino Acid Sequence
Our Abpromise guarantee covers the use of ab45439 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-BCAR3 antibody (ab21705)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- BCAR 3
FunctionMay act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins.
Tissue specificityUbiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue.
Sequence similaritiesContains 1 Ras-GEF domain.
Contains 1 SH2 domain.
- Information by UniProt
ab45439 has not yet been referenced specifically in any publications.