Description

Associated products

Specifications

Our Abpromise guarantee covers the use of ab237601 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Chromogranin A antibody (ab85554)

  • Form

    Lyophilised
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.

    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.

    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.

    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.

    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.

General Info

  • Alternative names

    • beta Granin
    • betagranin (N-terminal fragment of chromogranin A)
    • catestatin
    • CgA
    • CHG A
    • Chga
    • chromofungin
    • Chromogranin A
    • Chromogranin A parathyroid secretory protein 1
    • Chromogranin A precursor
    • ChromograninA
    • CMGA_HUMAN
    • ER-37
    • Pancreastatin
    • Parastatin
    • Parathyroid secretory protein 1
    • Pituitary secretory protein I
    • Secretory protein I
    • SP I
    • SP-I
    • SP1
    • SPI
    • Vasostatin
    • vasostatin 2
    • Vasostatin I
    • Vasostatin II
    • vasostatin-2
    see all
  • Function

    Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.
  • Sequence similarities

    Belongs to the chromogranin/secretogranin protein family.
  • Post-translational
    modifications

    Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
  • Cellular localization

    Secreted. Neuroendocrine and endocrine secretory granules.
  • Information by UniProt

References

ab237601 has not yet been referenced specifically in any publications.

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