Product nameHuman Complement Factor D Antibody Pair - BSA and Azide free
See all Factor D/CFD kits
Assay typeELISA set
Range15.63 pg/ml - 1000 pg/ml
Species reactivityReacts with: Human
The Antibody Pair can be used to quantify Human Complement Factor D. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.
For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab243686), which uses the same antibodies. However, due to differences in their formulation, this antibody pair cannot be used with the consumables provided with our SimpleStep ELISA Kits. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.
Download SDS here.
Tested applicationsSuitable for: Sandwich ELISAmore details
Storage instructionsStore at +4°C. Please refer to protocols.
Components 10 x 96 tests Human Complement Factor D Capture Antibody (unconjugated) 1 x 100µg Human Complement Factor D Detector Antibody (unconjugated) 1 x 100µg
FunctionFactor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Involvement in diseaseDefects in CFD are the cause of complement factor D deficiency (CFD deficiency) [MIM:134350]. CFD deficiency predisposes to invasive meningococcal disease.
Sequence similaritiesBelongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
- Information by UniProt
- Adipsin/complement factor D
Our Abpromise guarantee covers the use of ab256641 in the following tested applications.
|Sandwich ELISA||Use at an assay dependent concentration.|
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab256641 has not yet been referenced specifically in any publications.