Overview

  • Product name
    Human Detyrosinated alpha Tubulin peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab191559 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Detyrosinated alpha Tubulin antibody (ab48389)

  • Form
    Liquid
  • Additional notes

    This is an immunizing peptide for ab48389.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C long term.

    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.1% BSA

General Info

  • Alternative names
    • Alpha tubulin 1
    • TUBA1
    • TUBA2
    • TUBA3C
    • TUBA4A
    • Tubulin alpha 1
    • Tubulin alpha 1 chain
    • Tubulin alpha 1 testis specific
    • Tubulin, alpha 3c
    • Tubulin, alpha 4a
    see all
  • Relevance
    Microtubules are required for many well characterized functions in eukaryotic cells, including the movement of chromosomes in mitosis and meiosis, intracellular transport, establishment and maintenance of cellular morphology, cell growth, cell migration and morphogenesis in multicellular organisms. The building block of a microtubule is the tubulin subunit, a heterodimer of alpha and beta tubulin. Both of these monomers are found in all eukaryotes, and their sequences are highly conserved. The tubulin protein is a major target of drug molecules, and consequently, tubulin inhibitors have attracted great attention as antimitotic antitumor agents for chemotherapeutic use. This antibody recognizes detyrosinated alpha tubulin, a post translational modification of alpha tubulin.
  • Cellular localization
    Cytoplasmic

References

ab191559 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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