Product nameHuman DR3 peptide
See all DR3 proteins and peptides
Amino Acid Sequence
SequenceQGGTRSPRCDCAGDFH Amino acids 25 to 40 of human DR3 (1,2)
Amino acids25 to 40
Our Abpromise guarantee covers the use of ab8445 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
PBS with 0.1% BSA 0.02% sodium azide pH7.2
- Apo 3
FunctionReceptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
Tissue specificityAbundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
Sequence similaritiesContains 1 death domain.
Contains 4 TNFR-Cys repeats.
Cellular localizationSecreted and Cell membrane.
- Information by UniProt
ab8445 has not yet been referenced specifically in any publications.