Product nameHuman ENT1 peptide
See all ENT1 proteins and peptides
Amino Acid Sequence
Our Abpromise guarantee covers the use of ab48606 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-ENT1 antibody (ab48607)
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
- Equilibrative NBMPR-sensitive nucleoside transporter
- equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter
- Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter
FunctionMediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).
Tissue specificityExpressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.
Sequence similaritiesBelongs to the SLC29A transporter family.
Cellular localizationBasolateral cell membrane. Apical cell membrane. Predominantly localized in the basolateral membrane in polarised MDCK cells.
- Information by UniProt
ab48606 has not yet been referenced specifically in any publications.