Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-VRGRPIFWMEKDI
    • Amino acids
      274 to 286

Specifications

Our Abpromise guarantee covers the use of ab22969 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • AI225910
    • FUS 2
    • N acetyltransferase 6
    • NAT6
    • OTTMUSP00000046403
    • OTTMUSP00000046404
    • OTTMUSP00000046405
    • OTTMUSP00000046406
    • Protein fus 2
    • Protein fusion 2
    see all
  • Relevance
    FUS2 seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor. It is strongly expressed in heart and skeletal muscle, followed by brain and pancreas, with weak expression in kidney, liver, and lung and no expression in placenta. Defects in FUS2 are found in non-small cell lung cancer (NSCLC) cell lines.
  • Cellular localization
    Cytoplasmic

References

ab22969 has not yet been referenced specifically in any publications.

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