Product nameHuman GPCR GPR39 peptide
See all GPCR GPR39 proteins and peptides
Our Abpromise guarantee covers the use of ab39283 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
- G protein coupled receptor GPR39
- G Protein-Coupled Receptor 39
- G-protein coupled receptor 39
FunctionZn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death.
Tissue specificityExpressed in many tissues, including the stomach, intestine and hypothalamus.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab39283 has been referenced in 3 publications.
- Allouche-Fitoussi D et al. Signaling pathways involved in human sperm hyperactivated motility stimulated by Zn2. Mol Reprod Dev 86:502-515 (2019). PubMed: 30746812
- Alén BO et al. The role of the obestatin/GPR39 system in human gastric adenocarcinomas. Oncotarget 7:5957-71 (2016). PubMed: 26716511
- Metsuyanim S et al. Expression of stem cell markers in the human fetal kidney. PLoS One 4:e6709 (2009). PubMed: 19696931