Our Abpromise guarantee covers the use of ab90993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Form

  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names

    • AI385591
    • AI874987
    • Homeo box 4D
    • Homeo box D10
    • Homeobox D10
    • Homeobox protein Hox-4D
    • Homeobox protein Hox-4E
    • Homeobox protein Hox-D10
    • Hox 4.4
    • Hox 4.5
    • Hox 4D
    • Hox 4E
    • Hox 5.3
    • HOX4D
    • HOX4E
    • HOXD10
    • HXD10
    • HXD10_HUMAN
    • OTTMUSP00000017845
    • RP23-313J15.9
    see all
  • Function

    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • Tissue specificity

    Strongly expressed in the adult male and female urogenital tracts.
  • Involvement in disease

    Defects in HOXD10 are a cause of congenital vertical talus (CVT) [MIM:192950]; also known as rocker-bottom foot deformity or congenital convex pes valgus. CVT is a dislocation of the talonavicular joint, with rigid dorsal dislocation of the navicular over the neck of the talus. This condition is usually associated with multiple other congenital deformities and only rarely is an isolated deformity.
  • Sequence similarities

    Belongs to the Abd-B homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Developmental stage

    Expressed in the developing limb buds.
  • Cellular localization

  • Information by UniProt


ab90993 has not yet been referenced specifically in any publications.

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