Product nameHuman ICA 512 / PTPRN Antibody Pair - BSA and Azide free
See all ICA 512/PTPRN kits
Assay typeELISA set
Range31.25 pg/ml - 2000 pg/ml
Species reactivityReacts with: Human
The Antibody Pair can be used to quantify Human PTPRN. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.
For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab226903), which uses the same antibodies. However, due to differences in their formulation, this antibody pair cannot be used with the consumables provided with our SimpleStep ELISA Kits. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.
Download SDS here.
Tested applicationsSuitable for: Sandwich ELISAmore details
Storage instructionsStore at +4°C. Please refer to protocols.
Components 10 x 96 tests Human ICA 512 / PTPRN Capture Antibody (unconjugated) 1 x 100µg Human ICA 512 / PTPRN Detector Antibody (unconjugated) 1 x 100µg
FunctionImplicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
Tissue specificityExpression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.
Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
Contains 1 tyrosine-protein phosphatase domain.
modificationsAppears to undergo multiple proteolytic cleavage at consecutive basic residues.
Cellular localizationMembrane. Neuroendocrine secretory granules.
- Information by UniProt
- CA 512
- IA 2
Our Abpromise guarantee covers the use of ab244039 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Sandwich ELISA||Use at an assay dependent concentration.|
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab244039 has not yet been referenced specifically in any publications.