Overview

  • Product name

    Anti-Human IgG3 antibody [5G12]
    See all Human IgG3 primary antibodies
  • Description

    Mouse monoclonal [5G12] to Human IgG3
  • Host species

    Mouse
  • Specificity

    Subclass-specific for human IgG3. No allotype restriction. Hinge-region specific.
  • Tested applications

    Suitable for: ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    IgG3 from human serum.

  • General notes

    Concentration varies from lot to lot and can be provided on request.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.40
    Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Purification notes

    Chromatography on protein A Sepharose
  • Clonality

    Monoclonal
  • Clone number

    5G12
  • Myeloma

    Sp2/0
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab1928 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

Specific antibody titer is 1/300,000 by indirect ELISA.

Target

  • Relevance

    IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • DKFZp686H11213 antibody
    • FLJ39988 antibody
    • FLJ40036 antibody
    • FLJ40253 antibody
    • FLJ40587 antibody
    • FLJ40789 antibody
    • FLJ40834 antibody
    • G3m marker antibody
    • HDC antibody
    • Heavy chain disease protein antibody
    • Ig gamma 3 chain C region antibody
    • IgG3 antibody
    • IGHG 3 antibody
    • IGHG3 antibody
    • IGHG3 protein antibody
    • Immunoglobulin gamma 3 (Gm marker) antibody
    • Immunoglobulin gamma 3 antibody
    • Immunoglobulin heavy constant gamma 3 (G3m marker) antibody
    • Immunoglobulin heavy constant gamma 3 antibody
    • MGC45809 antibody
    see all

References

This product has been referenced in:

  • Nair M  et al. Dexamethasone-Mediated Upregulation of Calreticulin Inhibits Primary Human Glioblastoma Dispersal Ex Vivo. Int J Mol Sci 19:N/A (2018). Read more (PubMed: 29443896) »
  • Poitelon Y  et al. Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination. Nat Commun 6:8303 (2015). WB ; Rat . Read more (PubMed: 26383514) »
See all 3 Publications for this product

Customer reviews and Q&As

Question
Answer

Thank you for your enquiry. I have listed the concentrations below. Cat.# ab1928, lot 81191, conc. 3.00 mg/ml Cat.# ab1935, lot 74364, conc. 5.00 mg/ml Cat.# ab1930, lot 81196, conc. 6.30 mg/ml Cat.# ab1927, lot81198, conc. 3.70 mg/ml

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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