Overview

  • Product name

    Anti-Human IgG4 heavy chain antibody [5C7]
    See all Human IgG4 heavy chain primary antibodies
  • Description

    Mouse monoclonal [5C7] to Human IgG4 heavy chain
  • Host species

    Mouse
  • Specificity

    Subclass-specific for human IgG4. No allotype restriction. Fc-region specific.
  • Tested applications

    Suitable for: ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    IgG4 from human serum.

  • General notes

    Concentration varies from lot to lot and can be provided on request.

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.40
    Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Purification notes

    Chromatography on protein A Sepharose
  • Clonality

    Monoclonal
  • Clone number

    5C7
  • Myeloma

    Sp2/0
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab1930 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

Specific antibody titer is 1/100,000 by indirect ELISA.

Target

  • Relevance

    Immunoglobulin G (IgG), is one of the most abundant protein in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • AU044919 antibody
    • Gamma 2b immunoglobulin antibody
    • Ig gamma 4 chain C region antibody
    • Ighg 4 antibody
    • Ighg4 antibody
    • Immunoglobulin gamma 4 heavy chain antibody
    • Immunoglobulin heavy chain (gamma polypeptide 4) antibody
    • Immunoglobulin heavy chain gamma polypeptide antibody
    • Immunoglobulin heavy constant gamma 4 (G4m marker) antibody
    • MGC102604 antibody
    • MGC102659 antibody
    see all

References

This product has been referenced in:

  • Harlow DE  et al. Myelin Proteolipid Protein Complexes with av Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression. J Neurosci 35:12018-32 (2015). Read more (PubMed: 26311781) »
  • Medeiros MM  et al. Natural antibody response to Plasmodium falciparum merozoite antigens MSP5, MSP9 and EBA175 is associated to clinical protection in the Brazilian Amazon. BMC Infect Dis 13:608 (2013). ELISA ; Human . Read more (PubMed: 24373342) »
See all 2 Publications for this product

Customer reviews and Q&As

Answer

The concentration of the antibody is 7 mg/ml.

Read More

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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