Key features and details
- Mouse monoclonal [5C7] to Human IgG4 heavy chain
- Suitable for: ELISA
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-Human IgG4 heavy chain antibody [5C7]
See all Human IgG4 heavy chain primary antibodies
DescriptionMouse monoclonal [5C7] to Human IgG4 heavy chain
SpecificitySubclass-specific for human IgG4. No allotype restriction. Fc-region specific.
Tested applicationsSuitable for: ELISAmore details
Species reactivityReacts with: Human
IgG4 from human serum.
Concentration varies from lot to lot and can be provided on request.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.09% Sodium azide
Concentration information loading...
PurityProtein A purified
Purification notesChromatography on protein A Sepharose
Our Abpromise guarantee covers the use of ab1930 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent concentration.
Specific antibody titer is 1/100,000 by indirect ELISA.
RelevanceImmunoglobulin G (IgG), is one of the most abundant protein in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
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To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab1930 has been referenced in 2 publications.
- Harlow DE et al. Myelin Proteolipid Protein Complexes with av Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression. J Neurosci 35:12018-32 (2015). PubMed: 26311781
- Medeiros MM et al. Natural antibody response to Plasmodium falciparum merozoite antigens MSP5, MSP9 and EBA175 is associated to clinical protection in the Brazilian Amazon. BMC Infect Dis 13:608 (2013). ELISA ; Human . PubMed: 24373342