Description

  • Product name

    Human KIF4A/KIF4 peptide
  • Animal free

    No
  • Nature

    Synthetic
    • Species

      Human
    • Sequence

      SFFSGCSPIEEEAH
    • Amino acids

      1219 to 1232

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22955 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-KIF4A/KIF4 antibody (ab3815)

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names

    • Chromokinesin
    • Chromokinesin-A
    • Chromosome associated kinesin KIF4A
    • Chromosome-associated kinesin KIF4A
    • FLJ12530
    • FLJ12655
    • FLJ14204
    • FLJ20631
    • HSA271784
    • KIF4
    • KIF4 G1
    • KIF4A
    • KIF4A_HUMAN
    • KIF4G1
    • Kinesin family member 4A
    see all
  • Function

    Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.
  • Tissue specificity

    Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung.
  • Sequence similarities

    Belongs to the kinesin-like protein family. Chromokinesin subfamily.
    Contains 1 kinesin-motor domain.
  • Cellular localization

    Nucleus matrix. Cytoplasm > cytoskeleton > spindle. Midbody. Chromosome. Not present in the nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stages of mitosis.
  • Information by UniProt

References

ab22955 has not yet been referenced specifically in any publications.

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