Associated products


Our Abpromise guarantee covers the use of ab74029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Kindlin 2 antibody (ab74030)

  • Form

  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names

    • FLJ34213
    • FLJ44462
    • UNC112
    • Fermitin family homolog 2
    • Fermt2
    • KIND2
    • Kindlin-2
    • MIG-2
    • MIG2
    • Mitogen-inducible gene 2 protein
    • PH domain-containing family C member 1
    • Pleckstrin homology domain containing family C (with FERM domain) member 1
    • Pleckstrin homology domain-containing family C member 1
    • PLEKHC1
    • UNC112B
    see all
  • Function

    Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites.
  • Tissue specificity

    Ubiquitous. Found in numerous tumor tissues.
  • Sequence similarities

    Belongs to the kindlin family.
    Contains 1 FERM domain.
    Contains 1 PH domain.
  • Domain

    The FERM domain is not correctly detected by PROSITE or Pfam techniques because it contains the insertion of a PH domain.
  • Cellular localization

    Cytoplasm > cell cortex. Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Within actin stress fibers at cell-ECM focal adhesion sites.
  • Information by UniProt


ab74029 has not yet been referenced specifically in any publications.

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