Anti-Human placental lactogen (epitope 2) antibody [INN-hPL-37] (ab11396)
Key features and details
- Mouse monoclonal [INN-hPL-37] to Human placental lactogen (epitope 2)
- Suitable for: RIA
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-Human placental lactogen (epitope 2) antibody [INN-hPL-37] -
Description
Mouse monoclonal [INN-hPL-37] to Human placental lactogen (epitope 2) -
Host species
Mouse -
Specificity
Radioimmunological direct binding studies were performed with 125I-labelled. hPL, hGH, hPRL and increasing amounts of INN-hPL-37. In addition, competitive RIA with unlabelled hGH, hPRL and hPL were used for characterization. In competitive RIA cross reactivity with hGH and hPRL was below 1%. Direct binding demonstrated 39% reactivity with hGH but no cross reactivity with hPRL. -
Tested applications
Suitable for: RIAmore details -
Species reactivity
Reacts with: Human -
Immunogen
Other Immunogen Type corresponding to Human Human placental lactogen (epitope 2).
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General notes
This product should be stored undiluted. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.09% Sodium azide -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
Purification by affinity chromatography. -
Clonality
Monoclonal -
Clone number
INN-hPL-37 -
Myeloma
x63-Ag8.653 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab11396 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
RIA |
Use at an assay dependent concentration.
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Notes |
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RIA
Use at an assay dependent concentration. |
Target
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Relevance
Placental lactogen is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 1442 Human
- Entrez Gene: 1443 Human
- Omim: 150200 Human
- SwissProt: P01243 Human
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Alternative names
- choriomammotropin antibody
- Chorionic somatomammotropin A antibody
- Chorionic somatomammotropin hormone 1 (placental lactogen) antibody
see all
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (1)
ab11396 has been referenced in 1 publication.
- Jin F et al. Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis. Int J Mol Med 37:949-57 (2016). IF . PubMed: 26935516