Human proBNP peptide (ab42238)

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Key features and details

  • Purity: > 95% HPLC
  • Suitable for: Blocking

Description

  • Product name

    Human proBNP peptide

  • Purity

    > 95 % HPLC.

  • Animal free

    No

  • Nature

    Synthetic

    • Species

      Human

    • Sequence

      QVEQTSLEPLQESPRPTGVWKSREVA

    • Amino acids

      32 to 57

Specifications

Our Abpromise guarantee covers the use of ab42238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form

    Lyophilized
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Constituent: 0.1% Acetic acid

  • Reconstitution
    Resuspend in 0.1% acetic acid for required concentration (vial content is 0.1 mg).

General Info

  • Alternative names

    • ANFB_HUMAN
    • BNP
    • BNP(1-32)
    • BNP(5-29)
    • BNP-32
    • Brain type natriuretic peptide
    • Gamma brain natriuretic peptide
    • Gamma-brain natriuretic peptide
    • Natriuretic peptide precursor B
    • nppb
    • NT proBNP
    see all

  • Function

    Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

  • Tissue specificity

    Brain and also in atria, but at much lower levels than ANP.

  • Sequence similarities

    Belongs to the natriuretic peptide family.

  • Cellular localization

    Secreted.
  • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab42238? Please let us know so that we can cite the reference in this datasheet.

ab42238 has not yet been referenced specifically in any publications.

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