Overview

  • Product name
    Human proBNP peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      QVEQTSLEPLQESPRPTGVWKSREVA
    • Amino acids
      32 to 57

Associated products

Specifications

Our Abpromise guarantee covers the use of ab42238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-proBNP antibody (ab14352)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 0.1% Acetic acid

General Info

  • Alternative names
    • ANFB_HUMAN
    • BNP
    • BNP(1-32)
    • BNP(5-29)
    • BNP-32
    • Brain type natriuretic peptide
    • Gamma brain natriuretic peptide
    • Gamma-brain natriuretic peptide
    • Natriuretic peptide precursor B
    • nppb
    • NT proBNP
    see all
  • Function
    Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • Tissue specificity
    Brain and also in atria, but at much lower levels than ANP.
  • Sequence similarities
    Belongs to the natriuretic peptide family.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab42238 has not yet been referenced specifically in any publications.

Publishing research using ab42238? Please let us know so that we can cite the reference in this datasheet.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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