Human proBNP peptide (ab42238)

Our Abpromise guarantee covers the use of ab42238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Stability and Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Constituent: 0.1% Acetic acid

Alternative names
- ANFB_HUMAN
- BNP
- BNP(1-32)
- BNP(5-29)
- BNP-32
- Brain type natriuretic peptide
- Gamma brain natriuretic peptide
- Gamma-brain natriuretic peptide
- Natriuretic peptide precursor B
- nppb
- NT proBNP
see all
Function

Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Tissue specificity

Brain and also in atria, but at much lower levels than ANP.
Sequence similarities

Belongs to the natriuretic peptide family.
Cellular localization

Secreted.
Target information above from: UniProt accession P16860 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

ab42238 has not yet been referenced specifically in any publications.

Publishing research using ab42238? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"