Product nameHuman Rabenosyn 5 peptide
Amino Acid Sequence
Amino acids771 to 784
Our Abpromise guarantee covers the use of ab45507 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-Rabenosyn 5 antibody (ab21196)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
- 110 kDa protein
- FYVE finger containing Rab5 effector protein Rabenosyn 5
- FYVE finger-containing Rab5 effector protein rabenosyn-5
FunctionRab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).
Sequence similaritiesContains 1 C2H2-type zinc finger.
Contains 1 FYVE-type zinc finger.
Contains 1 UIM (ubiquitin-interacting motif) repeat.
Cellular localizationCell membrane. Early endosome membrane.
- Information by UniProt
Human Rabenosyn 5 peptide (ab45507) at 0.3 µg/ml +
A431 whole cell lysate (ab7909)
ab45507 has not yet been referenced specifically in any publications.