Product nameHuman RAIDD peptide
See all RAIDD proteins and peptides
Amino Acid Sequence
SequenceCAGDRLTGIPSHILNSSPSD Amino acids 99 to 117 of human RAIDD (1,2)
Amino acids99 to 117
Our Abpromise guarantee covers the use of ab8460 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
PBS with 0.1% BSA 0.02% sodium azide pH7.2
- CASP2 and RIPK1 domain containing adaptor with death domain
- Caspase and RIP adapter with death domain
- Caspase and RIP adaptor with death domain
FunctionApoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
Tissue specificityConstitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
Sequence similaritiesContains 1 CARD domain.
Contains 1 death domain.
DomainContains a death domain involved in the binding of RIP protein.
The CARD domain mediates the interaction with caspase-2.
- Information by UniProt
ab8460 has not yet been referenced specifically in any publications.