Human Retinoic Acid Receptor gamma 2 peptide (ab39774)
Key features and details
- Purity: > 90% SDS-PAGE
- Suitable for: Neutralising, Blocking
Description
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Product name
Human Retinoic Acid Receptor gamma 2 peptide -
Purity
> 90 % SDS-PAGE. -
Animal free
No -
Nature
Synthetic -
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Species
Human -
Sequence
RRLYGAAGPGAGLLRR -
Amino acids
13 to 28
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Specifications
Our Abpromise guarantee covers the use of ab39774 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Neutralising
Blocking
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
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ReconstitutionReconstitute with 0.1 ml of distilled water.
General Info
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Alternative names
- NR1B3
- Nuclear receptor subfamily 1 group B member 3
- RAR gamma
see all -
Function
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function. -
Sequence similarities
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
Domain
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab39774 has not yet been referenced specifically in any publications.