Overview

  • Product name

    Human Retinoic Acid Receptor gamma 2 peptide

Description

  • Nature

    Synthetic
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      RRLYGAAGPGAGLLRR
    • Amino acids

      13 to 28

Specifications

Our Abpromise guarantee covers the use of ab39774 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Neutralising

    Blocking

  • Purity

    > 90 % SDS-PAGE.

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.

  • Reconstitution
    Reconstitute with 0.1 ml of distilled water.

General Info

  • Alternative names

    • NR1B3
    • Nuclear receptor subfamily 1 group B member 3
    • RAR gamma
    • RAR gamma isoform 2
    • RAR gamma2
    • RAR-gamma
    • RARC
    • Rarg
    • RARG_HUMAN
    • retinoic acid nuclear receptor gamma variant 1
    • retinoic acid nuclear receptor gamma variant 2
    • Retinoic acid receptor gamma
    see all
  • Function

    Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
  • Sequence similarities

    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Domain

    Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt

References

ab39774 has not yet been referenced specifically in any publications.

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