Product nameHuman SARM peptide
See all SARM proteins and peptides
Our Abpromise guarantee covers the use of ab41853 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-SARM antibody (ab17812)
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.12% Monobasic dihydrogen sodium phosphate, 0.142% Dibasic monohydrogen sodium phosphate, 0.754% Sodium chloride, 0.1% BSA
FunctionInvolved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.
Tissue specificityPredominantly expressed in kidney and liver. Expressed at lower level in placenta.
Sequence similaritiesContains 2 SAM (sterile alpha motif) domains.
Contains 1 TIR domain.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab41853 has not yet been referenced specifically in any publications.