Key features and details
- Suitable for: Blocking, ELISA
Product nameHuman Semaphorin 3A peptide
See all Semaphorin 3A proteins and peptides
SequenceSemaphorin 3A synthetic peptide corresponds to amino acids in the central region of human Sema3A. This sequence is highly conserved in rat and mouse Sema3A, and has low homology to other semaphorin family members.
Our Abpromise guarantee covers the use of ab88818 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-Semaphorin 3A antibody (ab23393)
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.05% Sodium azide
- Coll 1
- Collapsin 1
RelevanceOne family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI anchored extracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A (Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co receptors, Neuropilin 1 and Plexin A1, are expressed on axons that regenerate up to the injured region, but do not cross this Sema3A containing region. Thus, Sema3A and its co receptors may have important roles in regulating axon guidance during neuronal development and after neuronal injury.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab88818 has been referenced in 1 publication.
- Kou K et al. Decreased expression of semaphorin-3A, a neurite-collapsing factor, is associated with itch in psoriatic skin. Acta Derm Venereol 92:521-8 (2012). PubMed: 22565412