Anti-Human Serum Albumin antibody [1A9] (HRP) (ab24438)

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Overview

  • Product name

    Anti-Human Serum Albumin antibody [1A9] (HRP)
    See all Human Serum Albumin primary antibodies

  • Description

    Mouse monoclonal [1A9] to Human Serum Albumin (HRP)

  • Host species

    Mouse

  • Conjugation

    HRP

  • Specificity

    No cross-reactivity with other human proteins tested.

  • Tested applications

    Suitable for: Sandwich ELISA, WB, ELISAmore details

  • Species reactivity

    Reacts with: Human
    Does not react with: Cow

  • Immunogen

    Human serum albumin.

Properties

Applications

Our Abpromise guarantee covers the use of ab24438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use at an assay dependent dilution. Can be used as Detection antibody with ab10241. Suitable for quantitative detection of HSA in serum and urine.
WB Use at an assay dependent dilution. Predicted molecular weight: 65 kDa.
ELISA Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [15C7] to Human Serum Albumin (ab10241).

Target

  • Function

    Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

  • Tissue specificity

    Plasma.

  • Involvement in disease

    Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

  • Sequence similarities

    Belongs to the ALB/AFP/VDB family.
    Contains 3 albumin domains.

  • Post-translational
    modifications

    Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
    Glycated in diabetic patients.
    Phosphorylation sites are present in the extracelllular medium.
    Acetylated on Lys-223 by acetylsalicylic acid.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    • Alternative names

      • alb antibody
      • ALBU_HUMAN antibody
      • Albumin (32 AA) antibody
      • Albumin (AA 34) antibody
      • Albumin antibody
      • Analbuminemia antibody
      • Bisalbuminemia antibody
      • Cell growth inhibiting protein 42 antibody
      • DKFZp779N1935 antibody
      • Dysalbuminemic hyperthyroxinemia antibody
      • Growth inhibiting protein 20 antibody
      • HSA antibody
      • Hyperthyroxinemia dysalbuminemic antibody
      • PRO0883 antibody
      • PRO0903 antibody
      • PRO1341 antibody
      • Serum albumin antibody
      see all

    References

    This product has been referenced in:

    • Coudron L  et al. Fully integrated digital microfluidics platform for automated immunoassay; A versatile tool for rapid, specific detection of a wide range of pathogens. Biosens Bioelectron 128:52-60 (2019). Read more (PubMed: 30634074) »
    See 1 Publication for this product

    Publishing research using ab24438? Please let us know so that we can cite the reference in this datasheet.

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