Anti-Human Serum Albumin antibody [1A9] (HRP) (ab24438)
- Datasheet
- References (1)
- Protocols
Overview
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Product name
Anti-Human Serum Albumin antibody [1A9] (HRP)
See all Human Serum Albumin primary antibodies -
Description
Mouse monoclonal [1A9] to Human Serum Albumin (HRP) -
Host species
Mouse -
Conjugation
HRP -
Specificity
No cross-reactivity with other human proteins tested. -
Tested applications
Suitable for: Sandwich ELISA, WB, ELISAmore details -
Species reactivity
Reacts with: Human
Does not react with: Cow -
Immunogen
Human serum albumin.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Ascites -
Purification notes
Purified from ascites. -
Clonality
Monoclonal -
Clone number
1A9 -
Myeloma
Sp2/0 -
Isotype
IgG2a -
Research areas
Associated products
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ELISA pair antibody
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Recombinant Protein
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Related Products
- TMB ELISA Substrate (Highest Sensitivity) (ab171522)
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Applications
Our Abpromise guarantee covers the use of ab24438 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Sandwich ELISA | Use at an assay dependent dilution. Can be used as Detection antibody with ab10241. Suitable for quantitative detection of HSA in serum and urine. | |
WB | Use at an assay dependent dilution. Predicted molecular weight: 65 kDa. | |
ELISA | Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [15C7] to Human Serum Albumin (ab10241). |
Target
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Function
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. -
Tissue specificity
Plasma. -
Involvement in disease
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. -
Sequence similarities
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. -
Post-translational
modificationsKenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 213 Human
- Omim: 103600 Human
- SwissProt: P02768 Human
- Unigene: 418167 Human
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Alternative names
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
see all
Protocols
References
This product has been referenced in:
- Coudron L et al. Fully integrated digital microfluidics platform for automated immunoassay; A versatile tool for rapid, specific detection of a wide range of pathogens. Biosens Bioelectron 128:52-60 (2019). Read more (PubMed: 30634074) »