Anti-Human Serum Albumin antibody (Biotin) (ab27632)
- Datasheet
- References
- Protocols
Overview
-
Product nameAnti-Human Serum Albumin antibody (Biotin)
See all Human Serum Albumin primary antibodies -
DescriptionGoat polyclonal to Human Serum Albumin (Biotin)
-
Host speciesGoat
-
ConjugationBiotin
-
Tested applicationsSuitable for: WB, ELISAmore details
-
Species reactivityReacts with: Human
-
Immunogen
Full length native protein (purified) (Human)
Properties
-
FormLiquid
-
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
-
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 50% Glycerol, 0.435% Sodium chloride -
Concentration information loading... -
PurityImmunogen affinity purified
-
Purification notesPurified by Human Albumin-SepharoseTM affinity column.
-
ClonalityPolyclonal
-
IsotypeIgG
-
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
Our Abpromise guarantee covers the use of ab27632 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | ||
| ELISA |
Application notes
ELISA: 1/5000 - 1/40000.
WB: 1/5000 - 1/40000. Predicted molecular weight: 69 kDa.
The antibody can be used for detection of human Albumin in plasma.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
WB: 1/5000 - 1/40000. Predicted molecular weight: 69 kDa.
The antibody can be used for detection of human Albumin in plasma.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
-
FunctionSerum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
-
Tissue specificityPlasma.
-
Involvement in diseaseDefects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
-
Sequence similaritiesBelongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. -
Post-translational
modificationsKenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid. -
Cellular localizationSecreted.
- Information by UniProt
-
Database links
- Entrez Gene: 213 Human
- Omim: 103600 Human
- SwissProt: P02768 Human
- Unigene: 418167 Human
-
Alternative names
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
see all
Protocols
Datasheets and documents
References
ab27632 has not yet been referenced specifically in any publications.
