Overview

  • Product name
    Anti-Human Serum Albumin antibody (Biotin)
    See all Human Serum Albumin primary antibodies
  • Description
    Goat polyclonal to Human Serum Albumin (Biotin)
  • Host species
    Goat
  • Conjugation
    Biotin
  • Specificity
    Monospecificity of this antibody has been determined by ELISA against normal human albumin.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab40378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    ELISA: 1/20000. WB: Use at an assay dependent dilution. Predicted molecular weight: 69 kDa. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
    • Tissue specificity
      Plasma.
    • Involvement in disease
      Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
    • Sequence similarities
      Belongs to the ALB/AFP/VDB family.
      Contains 3 albumin domains.
    • Post-translational
      modifications
      Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
      Glycated in diabetic patients.
      Phosphorylation sites are present in the extracelllular medium.
      Acetylated on Lys-223 by acetylsalicylic acid.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • alb antibody
      • ALBU_HUMAN antibody
      • Albumin (32 AA) antibody
      • Albumin (AA 34) antibody
      • Albumin antibody
      • Analbuminemia antibody
      • Bisalbuminemia antibody
      • Cell growth inhibiting protein 42 antibody
      • DKFZp779N1935 antibody
      • Dysalbuminemic hyperthyroxinemia antibody
      • Growth inhibiting protein 20 antibody
      • HSA antibody
      • Hyperthyroxinemia dysalbuminemic antibody
      • PRO0883 antibody
      • PRO0903 antibody
      • PRO1341 antibody
      • Serum albumin antibody
      see all

    References

    ab40378 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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