Name: Human SH3BP1 peptide
SKU: ab23182

Our Abpromise guarantee covers the use of ab23182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Stability and Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Alternative names
- 3BP 1
- 3BP-1
- 3BP1_HUMAN
- ARHGAP43
- dJ37E16
- FLJ21318
- OTTHUMP00000028981
- SH3 domain binding protein 1
- SH3 domain-binding protein 1
- Sh3bp1
see all
Function

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.
Sequence similarities

Contains 1 BAR domain.
Contains 1 Rho-GAP domain.
Target information above from: UniProt accession Q9Y3L3 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

ab23182 has not yet been referenced specifically in any publications.

Publishing research using ab23182? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Human SH3BP1 peptide (ab23182)