Description

  • Product name

    Human SNX18 peptide
  • Animal free

    No
  • Nature

    Synthetic
    • Species

      Human
    • Sequence

      C-KVQRVPLMTVLSF
    • Amino acids

      616 to 628

Specifications

Our Abpromise guarantee covers the use of ab22972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Reconstitution
    Reconstitute to 1mg/ml with 100ul water. (Lyophilised from water.)

General Info

  • Alternative names

    • FLJ11997
    • FLJ32560
    • FLJ61062
    • MGC150827
    • MGC150829
    • SH3 and PX domain containing protein 3B
    • SH3 and PX domain-containing protein 3B
    • SH3PX2
    • SH3PXD3B
    • SNAG 1
    • SNAG1
    • SNX18
    • SNX18_HUMAN
    • Sorting nexin 18
    • Sorting nexin associated golgi protein 1
    • Sorting nexin-18
    • Sorting nexin-associated Golgi protein 1
    see all
  • Function

    May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
  • Sequence similarities

    Belongs to the sorting nexin family.
    Contains 1 BAR domain.
    Contains 1 PX (phox homology) domain.
    Contains 1 SH3 domain.
  • Domain

    The PX domain mediates interaction with membranes enriched in phosphatidylinositol-4,5-bisphosphate.
  • Cellular localization

    Endomembrane system. Endosome membrane. Cell membrane. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation.
  • Information by UniProt

References

ab22972 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab22972.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up