Description

  • Product name

    Human SYN5 peptide
  • Animal free

    No
  • Nature

    Synthetic
    • Species

      Human
    • Sequence

      C-DSQSLARKYMYSS
    • Amino acids

      527 to 539

Specifications

Our Abpromise guarantee covers the use of ab23267 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form

    Lyophilised
  • Additional notes

    Previously labelled as Syntrophin gamma 2. 

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Reconstitution
    Reconstitute to 1mg/ml with water. (Lyophilised from water.)

General Info

  • Alternative names

    • 9530013L23
    • G2SYN
    • Gamma-2-syntrophin
    • Gamma2-syntrophin
    • SNTG2
    • SNTG2_HUMAN
    • SYN5
    • Syntrophin 5
    • Syntrophin gamma 2
    • Syntrophin-5
    see all
  • Function

    Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
  • Tissue specificity

    Widely expressed. Strong expression in brain and testis. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia.
  • Sequence similarities

    Belongs to the syntrophin family.
    Contains 1 PDZ (DHR) domain.
    Contains 1 PH domain.
  • Domain

    The association with dystrophin or related proteins probably leaves the PDZ domain available to recruit proteins to the membrane.
  • Cellular localization

    Cell membrane > sarcolemma. Cytoplasm > cytoskeleton. In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane.
  • Information by UniProt

References

ab23267 has not yet been referenced specifically in any publications.

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