Human TBL1 peptide (ab22881)
- Datasheet
- References
- Protocols
Description
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Product name
Human TBL1 peptide
See all TBL1 proteins and peptides -
Animal free
No -
Nature
Synthetic -
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Species
Human -
Sequence
SASDGSVCVLDLRK -
Amino acids
564 to 577
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Associated products
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Corresponding Antibody
Specifications
Our Abpromise guarantee covers the use of ab22881 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Blocking - Blocking peptide for Anti-TBL1 antibody (ab2243)
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
General Info
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Alternative names
- EBI
- F box like/WD repeat protein TBL1X
- F-box-like/WD repeat-containing protein TBL1X
see all -
Function
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. -
Tissue specificity
Ubiquitous. -
Sequence similarities
Belongs to the WD repeat EBI family.
Contains 1 F-box-like domain.
Contains 1 LisH domain.
Contains 8 WD repeats. -
Domain
The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes. -
Cellular localization
Nucleus. - Information by UniProt
Datasheets and documents
References
ab22881 has not yet been referenced specifically in any publications.
