- Datasheet
- Specific References
- Protocols
Overview
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Product nameHuman TBL1 peptide
See all TBL1 proteins and peptides
Description
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NatureSynthetic
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Amino Acid Sequence
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SpeciesHuman
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SequenceSASDGSVCVLDLRK
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Amino acids564 to 577
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Associated products
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Corresponding Antibody
Specifications
Our Abpromise guarantee covers the use of ab22881 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Blocking - Blocking peptide for Anti-TBL1 antibody (ab2243)
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FormLiquid
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
General Info
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Alternative names
- EBI
- F box like/WD repeat protein TBL1X
- F-box-like/WD repeat-containing protein TBL1X
see all -
FunctionF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
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Tissue specificityUbiquitous.
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Sequence similaritiesBelongs to the WD repeat EBI family.
Contains 1 F-box-like domain.
Contains 1 LisH domain.
Contains 8 WD repeats. -
DomainThe F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.
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Cellular localizationNucleus.
- Information by UniProt
References
ab22881 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"