Overview

  • Product name

    Human TIA1 Antibody Pair - BSA and Azide free
    See all TIA1 kits
  • Detection method

    Colorimetric
  • Assay type

    ELISA set
  • Range

    188 pg/ml - 12000 pg/ml
  • Species reactivity

    Reacts with: Human
  • Product overview

    The Antibody Pair can be used to quantify Human TIA1. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.


    For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab231921), which uses the same antibodies. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.


    To receive an electronic copy of the Certificate of Analysis, please send an email to technical support with "CoA for matched antibody pair kit" in the subject line and the desired product number and lot number in the body of the email.


    Download SDS here.


     

  • Tested applications

    Suitable for: ELISAmore details
  • Platform

    Reagents

Properties

  • Storage instructions

    Store at +4°C. Please refer to protocols.
  • Components 10 x 96 tests
    Human TIA1 Capture Antibody 1 x 100µg
    Human TIA1 Detector Antibody 1 x 100µg
  • Research areas

  • Function

    Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
  • Sequence similarities

    Contains 3 RRM (RNA recognition motif) domains.
  • Cellular localization

    Cytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage.
  • Information by UniProt
  • Alternative names

    • Cytotoxic granule associated RNA binding protein
    • Cytotoxic granule associated RNA binding protein 1
    • mTIA-1
    • Nucleolysin TIA 1 isoform p40
    • Nucleolysin TIA-1 isoform p40
    • Nucleolysin TIA1 isoform p40
    • p40 TIA 1
    • p40-TIA-1
    • p40-TIA-1 (containing p15-TIA-1)
    • RNA binding protein TIA 1
    • RNA binding protein TIA1
    • RNA-binding protein TIA-1
    • T-cell-restricted intracellular antigen-1
    • Tia
    • TIA 1
    • TIA 1 cytotoxic granule associated RNA binding protein
    • TIA-1
    • TIA1
    • TIA1 cytotoxic granule associated RNA binding protein
    • TIA1 cytotoxic granule associated RNA binding protein like 1
    • TIA1 protein
    • TIA1_HUMAN
    • TIAL1
    • TIAR
    • WDM
    see all
  • Database links

Associated products

Applications

Our Abpromise guarantee covers the use of ab244072 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

References

ab244072 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab244072.
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