Product nameHuman TIA1 peptide
See all TIA1 proteins and peptides
Our Abpromise guarantee covers the use of ab41475 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-TIA1 antibody - C-terminal (ab40693)
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
- Cytotoxic granule associated RNA binding protein
- Cytotoxic granule associated RNA binding protein 1
FunctionInvolved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
Sequence similaritiesContains 3 RRM (RNA recognition motif) domains.
Cellular localizationCytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage.
- Information by UniProt
ab41475 has not yet been referenced specifically in any publications.