Key features and details
- Expression system: Synthetic
- Purity: > 90% HPLC
- Suitable for: Blocking
Product nameHuman UCP1 peptide
See all UCP1 proteins and peptides
Purity> 90 % HPLC.
Additional sequence informationSynthetic peptide corresponding to Human UCP1 aa 100-200, the exact sequence is proprietary information.
Our Abpromise guarantee covers the use of ab24282 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-UCP1 antibody (ab23841)
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Information available upon request.
- mitochondrial brown fat uncoupling protein
- Mitochondrial brown fat uncoupling protein 1
FunctionUCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
Tissue specificityBrown adipose tissue.
Sequence similaritiesBelongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.
Cellular localizationMitochondrion inner membrane.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab24282 has been referenced in 2 publications.
- Kawashima M et al. Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells. Cancer Metab 8:13 (2020). PubMed: 32647572
- Pearson LE et al. To each its own: Thermoregulatory strategy varies among neonatal polar phocids. Comp Biochem Physiol A Mol Integr Physiol 178:59-67 (2014). Blocking . PubMed: 25151642