Human V2R peptide (ab192052)

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Key features and details

  • Suitable for: Blocking

Description

  • Product name

    Human V2R peptide

  • Accession

    P30518

  • Animal free

    No

  • Nature

    Synthetic

    • Species

      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab192052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-V2R antibody (ab188748)

  • Form

    Liquid

  • Additional notes

    This is the blocking peptide for ab188748

     This product was previously labelled as AVPR V2

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

    Constituent: PBS

General Info

  • Alternative names

    • ADHR
    • Antidiuretic hormone receptor
    • Arginine vasopressin receptor 2
    • AVP R2
    • AVPR 2
    • AVPR V2
    • AVPR2
    • DI1
    • DIR
    • DIR 3
    • DIR3
    • MGC126533
    • MGC138386
    • NDI
    • Nephrogenic diabetes insipidus
    • Renal type arginine vasopressin receptor
    • Renal-type arginine vasopressin receptor
    • V2 receptor
    • V2R
    • V2R_HUMAN
    • Vasopressin V2
    • Vasopressin V2 receptor
    see all

  • Function

    Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

  • Tissue specificity

    Kidney.

  • Involvement in disease

    Defects in AVPR2 are the cause of nephrogenic syndrome of inappropriate antidiuresis (NSIAD) [MIM:300539]. This disorder is characterized by an inability to excrete a free water load, with inappropriately concentrated urine and resultant hyponatremia, hypoosmolarity, and natriuresis.
    Defects in AVPR2 are the cause of diabetes insipidus nephrogenic X-linked (XNDI) [MIM:304800]; also known as diabetes insipidus nephrogenic type 1. XNDI is caused by the inability of the renal collecting ducts to absorb water in response to arginine vasopressin. It is characterized by excessive water drinking (polydypsia), excessive urine excretion (polyuria), persistent hypotonic urine, and hypokalemia.

  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab192052? Please let us know so that we can cite the reference in this datasheet.

ab192052 has not yet been referenced specifically in any publications.

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