Overview

  • Product name

  • Description

    Goat polyclonal to HYAL2
  • Host species

    Goat
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human HYAL2 aa 2-12 (N terminal). (NP_003764.3).
    Sequence:

    RAGPGPTVTLAC


    Database link: Q12891

  • Positive control

    • IHC: Human kidney tissue.
  • General notes

    Reported variants NP_003764 and NP_149348 represent identical proteins.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, Tris buffered saline
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab223246 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab223246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3 - 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.
  • Tissue specificity

    Widely expressed. No expression detected in adult brain.
  • Sequence similarities

    Belongs to the glycosyl hydrolase 56 family.
    Contains 1 EGF-like domain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Hyal 2 antibody
    • Hyal-2 antibody
    • Hyal2 antibody
    • HYAL2_HUMAN antibody
    • Hyaluronidase 2 antibody
    • Hyaluronidase 2 Precursor antibody
    • Hyaluronidase-2 antibody
    • Hyaluronoglucosaminidase 2 antibody
    • Hyaluronoglucosaminidase-2 antibody
    • LUCA 2 antibody
    • LUCA-2 antibody
    • LUCA2 antibody
    • Lung carcinoma protein 2 antibody
    • lysosomal hyaluronidase antibody
    • PH 20 homolog antibody
    • PH-20 homolog antibody
    • PH20 homolog antibody
    see all

Images

  • Paraffin-embedded human kidney tissue stained for HYAL2 with ab223246 at 3.8 μg/ml in immunohistochemical analysis, followed by AP-staining.

References

ab223246 has not yet been referenced specifically in any publications.

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