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    hyaluronic-acid-sodium-salt-extracellular-matrix-component-ab143634.pdf

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Hyaluronic acid sodium salt, Extracellular matrix component (ab143634)

  • Datasheet
  • SDS
Submit a review Q&A (1)References (1)

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Chemical Structure - Hyaluronic acid sodium salt, Extracellular matrix component (ab143634)

    Key features and details

    • Extracellular matrix component. Cell-cell and cell-substrate adhesion mediator.
    • CAS Number: 9067-32-7
    • Purity: > 95%
    • Soluble in water (5 mg/ml)

    • Form / State: Solid
    • Source: Streptococcus sp.

    Overview

    • Product name

      Hyaluronic acid sodium salt, Extracellular matrix component
    • Description

      Extracellular matrix component. Cell-cell and cell-substrate adhesion mediator.
    • Biological description

      Extracellular matrix component. Cell-cell and cell-substrate adhesion mediator. Binds to CD44 and ICAM-1 receptors. Forms a viscoelastic solution in water. Mediates cell aggregation, migration, proliferation and activation in vivo. Orally active.
    • Purity

      > 95%
    • General notes

      Molecular Weight: ~1,000,000

    • CAS Number

      9067-32-7
    • Chemical structure

      Chemical Structure

    Properties

    • Chemical name

      Poly(β-glucuronic acid-[1→3]-β-N-acetylglucosamine-[1→4]), alternating

    • Storage instructions

      Store at Room Temperature. The product can be stored for up to 12 months.
    • Solubility overview

      Soluble in water (5 mg/ml)

    • Handling

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • Source

      Streptococcus sp.

    • Research areas

      • Biochemicals
      • Product Range
      • New
      • Biochemicals
      • Product Range
      • Just Add Water
      • Biochemicals
      • Chemical Type
      • Biochemicals
      • Biochemicals
      • Pharmacology
      • Signaling
      • Extracellular matrix & cell adhesion
      • Cell adhesion

    Images

    • Chemical Structure - Hyaluronic acid sodium salt, Extracellular matrix component (ab143634)
      Chemical Structure - Hyaluronic acid sodium salt, Extracellular matrix component (ab143634)
      2D chemical structure image of ab143634, Hyaluronic acid sodium salt, Extracellular matrix component

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (1)

    Publishing research using ab143634? Please let us know so that we can cite the reference in this datasheet.

    ab143634 has been referenced in 1 publication.

    • Huang L  et al. Local injection of high-molecular hyaluronan promotes wound healing in old rats by increasing angiogenesis. Oncotarget 9:8241-8252 (2018). PubMed: 29492191

    Customer reviews and Q&As

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    Question

    What is the molecular weight of the product Hyaluronic acid sodium salt (ab143634)?

    Read More

    Abcam community

    Verified customer

    Asked on Sep 29 2014

    Answer

    Hyaluronic Acid Sodium Salt is a linear heteropolysaccharide with repeating 3-O-(ß-D-glucuronido)-N-acetyl-D-glucosamine units linked by ß-(1-->4)) hexosaminidic bonds [C14H22NNaO11]n. Molecular weights of hyaluronic acids vary from 0.1-10 million, depending on the source. The hyaluronic acid from rooster comb is expected to have a molecular weight of 1-4 million. We list the formula weight as 1.65 million (1650 kDa).

    Read More

    Elisa Thomas

    Abcam Scientific Support

    Answered on Sep 29 2014

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