Product nameHydroxynonenal modified Bovine Serum Albumin
See all Bovine Serum Albumin proteins and peptides
Protein lengthFull length protein
Predicted molecular weight69 kDa
Our Abpromise guarantee covers the use of ab194193 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-4 Hydroxynonenal antibody (ab46545)
This can be used to block ab46545.
Modifications on lysine residues, with formation of carboxylmethyl-lysine (CML), malondialdehyde (MDA) and hexitol-lysine are advanced glycation end-products (AGE), and the coupling with reactive aldehyde compounds, such as 4-hydroxynonenal (4-HNE) may appear from lipid oxidation (Guichardant et al., 1998). These modifications feature the oxidative byproducts which react with NH2 groups and form Schiff-base adducts (Mark et al., 1996).
LDL treated with HNE or oxidatively modified by Cu++ or by cultured endothelial cells give rise to Michael addition-type HNE adducts that are recognized by HNE-specific antibodies.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Sodium azide
Constituents: PBS, 0.87% Sodium chloride, 0.01% EDTA
- Information by UniProt
ab194193 has not yet been referenced specifically in any publications.