Hyodeoxycholic acid (HDCA), Secondary bile acid (ab143131)

Overview

  • Product name

    Hyodeoxycholic acid (HDCA), Secondary bile acid
  • Description

    Secondary bile acid
  • Biological description

    Secondary bile acid. Lowers LDL-cholesterol concentration. Inhibits atherosclerotic lesion formation in vivo.
  • CAS Number

    83-49-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (4R)-4-[(3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-Dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
  • Molecular weight

    392.57
  • Molecular formula

    C24H40O4
  • PubChem identifier

    5283820
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(CCC(=O)O)C1CCC2C1(CCC3C2CC(C4C3(CCC(C4)O)C)O)C
  • Source

    Synthetic

References

This product has been referenced in:

  • Shih DM  et al. Hyodeoxycholic acid improves HDL function and inhibits atherosclerotic lesion formation in LDLR-knockout mice. FASEB J 27:3805-17 (2013). Read more (PubMed: 23752203) »
  • Cohen-Solal C  et al. Effects of hyodeoxycholic acid and alpha-hyocholic acid, two 6 alpha-hydroxylated bile acids, on cholesterol and bile acid metabolism in the hamster. Biochim Biophys Acta 1257:189-97 (1995). Read more (PubMed: 7619860) »

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