Overview

  • Product name

    Hypoxanthine, Purine derivative
  • Description

    Purine derivative. Inosine derivative.
  • Biological description

    Purine derivative. Inosine (ab120724) metabolite. Extracellular modulatory signal. Ischemia marker. Shows neuroprotective anti-inflammatory and trophic effects in vivo.
  • Purity

    > 98%
  • CAS Number

    68-94-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3,7-dihydropurin-6-one
  • Molecular weight

    136.11
  • Molecular formula

    C5H4N4O
  • PubChem identifier

    790
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO and in 1 N NaOH to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=NC2=C(N1)C(=O)N=CN2
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Cipriani S  et al. Protection by inosine in a cellular model of Parkinson's disease. Neuroscience : (2014). Read more (PubMed: 24880154) »
  • Yamamoto T  et al. Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid). Clin Chim Acta 356:35-57 (2005). Read more (PubMed: 15936302) »
  • Hagberg H  et al. Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia. J Neurochem 49:227-31 (1987). Read more (PubMed: 3585332) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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