Overview

  • Product name

    Anti-I-FABP antibody [EPR7136]
    See all I-FABP primary antibodies
  • Description

    Rabbit monoclonal [EPR7136] to I-FABP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human I-FABP. The exact sequence is proprietary.

  • Positive control

    • Human, Rat and Mouse small intestine lysates.
  • General notes

     

     

    Previously labelled as intestinal FABP.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab128860 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 15 kDa.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function

      FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
    • Tissue specificity

      Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.
    • Sequence similarities

      Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
    • Domain

      Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
    • Cellular localization

      Cytoplasm.
    • Information by UniProt
    • Database links

    • Alternative names

      • FABP 2 antibody
      • FABP2 antibody
      • FABPI antibody
      • FABPI_HUMAN antibody
      • Fatty acid binding protein 2 intestinal antibody
      • Fatty acid binding protein antibody
      • Fatty acid binding protein intestinal antibody
      • Fatty acid-binding protein 2 antibody
      • Fatty acid-binding protein antibody
      • I FABP antibody
      • I-FABP antibody
      • IFABP antibody
      • intestinal antibody
      • intestinal FABP antibody
      • Intestinal fatty acid binding protein 2 antibody
      • Intestinal-type fatty acid-binding protein antibody
      • MGC133132 antibody
      • OTTHUMP00000163925 antibody
      see all

    Images

    • All lanes : Anti-I-FABP antibody [EPR7136] (ab128860) at 1/1000 dilution

      Lane 1 : Human small intestine lysate
      Lane 2 : Rat small intestine lysate
      Lane 3 : Mouse small intestine lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 15 kDa

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    This product has been referenced in:

    • Costa DK  et al. Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice. Am J Physiol Endocrinol Metab 311:E105-16 (2016). Read more (PubMed: 27166280) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab128860.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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