Anti-Iba1 antibody (ab5076)

Goat polyclonal Iba1 antibody. Validated in WB, IHC, ICC, EM, ICC/IF and tested in Rat, Rabbit, Guinea pig, Cow, Dog, Human, Pig, Common marmoset. Cited in 316 publication(s). Independently reviewed.

Publishing research using ab5076? Please let us know so that we can cite the reference in this datasheet.

ab5076 has been referenced in 336 publications.

  • Hussain T  et al. Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus. Neurobiol Dis 121:163-176 (2019). PubMed: 30290271
  • Skowronska K  et al. Persistent Overexposure to N-Methyl-D-Aspartate (NMDA) Calcium-Dependently Downregulates Glutamine Synthetase, Aquaporin 4, and Kir4.1 Channel in Mouse Cortical Astrocytes. Neurotox Res 35:271-280 (2019). PubMed: 30220059
  • Wixey JA  et al. Neuropathology in intrauterine growth restricted newborn piglets is associated with glial activation and proinflammatory status in the brain. J Neuroinflammation 16:5 (2019). PubMed: 30621715
  • Sun HJ  et al. A Novel Synthetic Steroid of 2ß,3a,5a-Trihydroxy-androst-6-one Alleviates the Loss of Rat Retinal Ganglion Cells Caused by Acute Intraocular Hypertension via Inhibiting the Inflammatory Activation of Microglia. Molecules 24:N/A (2019). PubMed: 30641903
  • Liu W  et al. Mesenchymal stem cells alleviate the early brain injury of subarachnoid hemorrhage partly by suppression of Notch1-dependent neuroinflammation: involvement of Botch. J Neuroinflammation 16:8 (2019). PubMed: 30646897
  • Buscemi L  et al. Spatio-temporal overview of neuroinflammation in an experimental mouse stroke model. Sci Rep 9:507 (2019). PubMed: 30679481
  • Rosenzweig N  et al. PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model. Nat Commun 10:465 (2019). PubMed: 30692527
  • Ni H  et al. Exosomes Derived From Bone Mesenchymal Stem Cells Ameliorate Early Inflammatory Responses Following Traumatic Brain Injury. Front Neurosci 13:14 (2019). PubMed: 30733666
  • Liu L  et al. Icariin and icaritin ameliorated hippocampus neuroinflammation via inhibiting HMGB1-related pro-inflammatory signals in lipopolysaccharide-induced inflammation model in C57BL/6?J mice. Int Immunopharmacol 68:95-105 (2019). PubMed: 30616172
  • Piazza FV  et al. Severe Uncontrolled Maternal Hyperglycemia Induces Microsomia and Neurodevelopment Delay Accompanied by Apoptosis, Cellular Survival, and Neuroinflammatory Deregulation in Rat Offspring Hippocampus. Cell Mol Neurobiol 39:401-414 (2019). PubMed: 30739252
  • Li L  et al. Fisetin rescues retinal functions by suppressing inflammatory response in a DBA/2J mouse model of glaucoma. Doc Ophthalmol 138:125-135 (2019). PubMed: 30756213
  • Moriarty O  et al. Priming of Adult Incision Response by Early-Life Injury: Neonatal Microglial Inhibition Has Persistent But Sexually Dimorphic Effects in Adult Rats. J Neurosci 39:3081-3093 (2019). PubMed: 30796159
  • van de Looij Y  et al. Nutritional Intervention for Developmental Brain Damage: Effects of Lactoferrin Supplementation in Hypocaloric Induced Intrauterine Growth Restriction Rat Pups. Front Endocrinol (Lausanne) 10:46 (2019). PubMed: 30800096
  • Hu J  et al. Calpain inhibitor MDL28170 improves the transplantation-mediated therapeutic effect of bone marrow-derived mesenchymal stem cells following traumatic brain injury. Stem Cell Res Ther 10:96 (2019). PubMed: 30876457
  • Jendresen C  et al. Systemic LPS-induced Aß-solubilization and clearance in AßPP-transgenic mice is diminished by heparanase overexpression. Sci Rep 9:4600 (2019). PubMed: 30872722
  • Birla H  et al. Tinospora cordifolia Suppresses Neuroinflammation in Parkinsonian Mouse Model. Neuromolecular Med 21:42-53 (2019). PubMed: 30644041
  • Girolamo F  et al. Defining the role of NG2-expressing cells in experimental models of multiple sclerosis. A biofunctional analysis of the neurovascular unit in wild type and NG2 null mice. PLoS One 14:e0213508 (2019). PubMed: 30870435
  • Xu SY  et al. Regional and Cellular Mapping of Sortilin Immunoreactivity in Adult Human Brain. Front Neuroanat 13:31 (2019). PubMed: 30914927
  • Burston JJ  et al. The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation. Pain 160:658-669 (2019). PubMed: 30779717
  • O'Neill E  et al. L-alpha-aminoadipic acid restricts dopaminergic neurodegeneration and motor deficits in an inflammatory model of Parkinson's disease in male rats. J Neurosci Res 97:804-816 (2019). PubMed: 30924171
  • Thomi G  et al. Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury. Stem Cell Res Ther 10:105 (2019). PubMed: 30898154
  • Lu X  et al. Deficiency of a1,6-fucosyltransferase promotes neuroinflammation by increasing the sensitivity of glial cells to inflammatory mediators. Biochim Biophys Acta Gen Subj 1863:598-608 (2019). PubMed: 30572004
  • Liu FY  et al. Fluoxetine attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage: a possible role for the regulation of TLR4/MyD88/NF-?B signaling pathway. J Neuroinflammation 15:347 (2018). PubMed: 30572907
  • Zhou F  et al. Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage. Brain Behav Immun N/A:N/A (2018). PubMed: 30597199
  • Luan Y  et al. Codonopis bulleynana Forest ex Diels inhibits autophagy and induces apoptosis of colon cancer cells by activating the NF-?B signaling pathway. Int J Mol Med 41:1305-1314 (2018). PubMed: 29286074
  • Dzyubenko E  et al. Topological remodeling of cortical perineuronal nets in focal cerebral ischemia and mild hypoperfusion. Matrix Biol 74:121-132 (2018). PubMed: 30092283
  • Hoshi S  et al. Patching retinal breaks with polyethylene glycol-based synthetic hydrogel sealant for retinal detachment in rabbits. Exp Eye Res 177:117-121 (2018). PubMed: 30096324
  • Lu HF  et al. A new central post-stroke pain rat model: autologous blood injected thalamic hemorrhage involved increased expression of P2X4 receptor. Neurosci Lett 687:124-130 (2018). PubMed: 30267847
  • Aboulhoda BE & Hassan SS Effect of prenatal tramadol on postnatal cerebellar development: Role of oxidative stress. J Chem Neuroanat 94:102-118 (2018). PubMed: 30342117
  • Witcher KG  et al. Traumatic brain injury-induced neuronal damage in the somatosensory cortex causes formation of rod-shaped microglia that promote astrogliosis and persistent neuroinflammation. Glia 66:2719-2736 (2018). PubMed: 30378170
  • Wang W  et al. Minocycline Attenuates Stress-Induced Behavioral Changes via Its Anti-inflammatory Effects in an Animal Model of Post-traumatic Stress Disorder. Front Psychiatry 9:558 (2018). PubMed: 30459654
  • Morin-Brureau M  et al. Microglial phenotypes in the human epileptic temporal lobe. Brain 141:3343-3360 (2018). PubMed: 30462183
  • Woodward NC  et al. Prenatal and early life exposure to air pollution induced hippocampal vascular leakage and impaired neurogenesis in association with behavioral deficits. Transl Psychiatry 8:261 (2018). PubMed: 30498214
  • Takamori Y  et al. Differential expression of nuclear lamin subtypes in the neural cells of the adult rat cerebral cortex. IBRO Rep 5:99-109 (2018). PubMed: 30505974
  • Ibrahim SIA  et al. Mineralocorticoid Antagonist Improves Glucocorticoid Receptor Signaling and Dexamethasone Analgesia in an Animal Model of Low Back Pain. Front Cell Neurosci 12:453 (2018). PubMed: 30524245
  • Dietrich J  et al. Bone marrow drives central nervous system regeneration after radiation injury. J Clin Invest 128:281-293 (2018). PubMed: 29202481
  • Zukor K  et al. Zika virus-induced acute myelitis and motor deficits in adult interferon aß/? receptor knockout mice. J Neurovirol 24:273-290 (2018). PubMed: 29476408
  • Kemp KC  et al. Bone marrow transplantation stimulates neural repair in Friedreich's ataxia mice. Ann Neurol 83:779-793 (2018). PubMed: 29534309
  • Adamski MG  et al. Vascular Cognitive Impairment Linked to Brain Endothelium Inflammation in Early Stages of Heart Failure in Mice. J Am Heart Assoc 7:N/A (2018). PubMed: 29581224
  • Li C  et al. Disruption of glial cell development by Zika virus contributes to severe microcephalic newborn mice. Cell Discov 4:43 (2018). PubMed: 30083387
  • Tang MM  et al. Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression. Front Cell Neurosci 12:255 (2018). PubMed: 30135647
  • Vetreno RP  et al. Persistent Adult Neuroimmune Activation and Loss of Hippocampal Neurogenesis Following Adolescent Ethanol Exposure: Blockade by Exercise and the Anti-inflammatory Drug Indomethacin. Front Neurosci 12:200 (2018). PubMed: 29643762
  • Mukhamedshina YO  et al. Adipose-Derived Mesenchymal Stem Cell Application Combined With Fibrin Matrix Promotes Structural and Functional Recovery Following Spinal Cord Injury in Rats. Front Pharmacol 9:343 (2018). PubMed: 29692732
  • Li Q  et al. Phosphodiesterase-4 inhibition confers a neuroprotective efficacy against early brain injury following experimental subarachnoid hemorrhage in rats by attenuating neuronal apoptosis through the SIRT1/Akt pathway. Biomed Pharmacother 99:947-955 (2018). IHC-Fr ; Rat . PubMed: 29710495
  • Arango-Lievano M  et al. Topographic Reorganization of Cerebrovascular Mural Cells under Seizure Conditions. Cell Rep 23:1045-1059 (2018). IHC (PFA fixed) ; Mouse . PubMed: 29694884
  • Clayton AM  et al. Postpartum increases in cerebral edema and inflammation in response to placental ischemia during pregnancy. Brain Behav Immun 70:376-389 (2018). WB ; Rat . PubMed: 29588233
  • Bird EV  et al. A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability. Neuroscience 379:334-349 (2018). PubMed: 29588250
  • Yssel JD  et al. Treatment with the noradrenaline re-uptake inhibitor atomoxetine alone and in combination with the a2-adrenoceptor antagonist idazoxan attenuates loss of dopamine and associated motor deficits in the LPS inflammatory rat model of Parkinson's disease. Brain Behav Immun 69:456-469 (2018). IHC-P . PubMed: 29339319
  • Rahbardar MG  et al. Rosmarinic acid attenuates development and existing pain in a rat model of neuropathic pain: An evidence of anti-oxidative and anti-inflammatory effects. Phytomedicine 40:59-67 (2018). WB . PubMed: 29496176
  • Tzeng TT  et al. The Cyanthin Diterpenoid and Sesterterpene Constituents of Hericium erinaceus Mycelium Ameliorate Alzheimer's Disease-Related Pathologies in APP/PS1 Transgenic Mice. Int J Mol Sci 19:N/A (2018). PubMed: 29463001
  • Giurisato E  et al. Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proc Natl Acad Sci U S A 115:E2801-E2810 (2018). PubMed: 29507229
  • Liu D  et al. Endoplasmic Reticulum Stress in Spinal Cord Contributes to the Development of Morphine Tolerance. Front Mol Neurosci 11:72 (2018). PubMed: 29559889
  • Wu J  et al. Neuroprotective effect of dexmedetomidine in a murine model of traumatic brain injury. Sci Rep 8:4935 (2018). PubMed: 29563509
  • Jung M  et al. Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons. Mol Autism 9:20 (2018). PubMed: 29588831
  • Hong DK  et al. Combined Treatment With Dichloroacetic Acid and Pyruvate Reduces Hippocampal Neuronal Death After Transient Cerebral Ischemia. Front Neurol 9:137 (2018). PubMed: 29593636
  • Bruce KD  et al. Lipoprotein Lipase Is a Feature of Alternatively-Activated Microglia and May Facilitate Lipid Uptake in the CNS During Demyelination. Front Mol Neurosci 11:57 (2018). PubMed: 29599706
  • Fan XC  et al. Hypersensitivity of Prelimbic Cortex Neurons Contributes to Aggravated Nociceptive Responses in Rats With Experience of Chronic Inflammatory Pain. Front Mol Neurosci 11:85 (2018). PubMed: 29623029
  • Zhou R  et al. Activation of spinal dorsal horn P2Y13 receptors can promote the expression of IL-1ß and IL-6 in rats with diabetic neuropathic pain. J Pain Res 11:615-628 (2018). PubMed: 29628771
  • Ugras S  et al. Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in a-Synuclein Aggregation Disorders. EBioMedicine 31:307-319 (2018). IHC-P ; Human . PubMed: 29759483
  • Sun J  et al. Necrotizing enterocolitis is associated with acute brain responses in preterm pigs. J Neuroinflammation 15:180 (2018). IHC-P ; Rat . PubMed: 29885660
  • Garrett N  et al. Pravastatin therapy during preeclampsia prevents long-term adverse health effects in mice. JCI Insight 3:N/A (2018). PubMed: 29669946
  • Meng C  et al. A modified immunofluorescence in situ hybridization method to detect long non-coding RNAs and proteins in frozen spinal cord sections. Exp Ther Med 15:4623-4628 (2018). PubMed: 29805478
  • Thakkar R  et al. 17ß-Estradiol Regulates Microglia Activation and Polarization in the Hippocampus Following Global Cerebral Ischemia. Oxid Med Cell Longev 2018:4248526 (2018). PubMed: 29849895
  • Karthikeyan A  et al. Microglial SMAD4 regulated by microRNA-146a promotes migration of microglia which support tumor progression in a glioma environment. Oncotarget 9:24950-24969 (2018). PubMed: 29861845
  • Rueda N  et al. Anti-IL17 treatment ameliorates Down syndrome phenotypes in mice. Brain Behav Immun N/A:N/A (2018). PubMed: 29758264
  • Langley MR  et al. Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity. Neurotoxicology 64:240-255 (2018). PubMed: 28595911
  • Li Y  et al. Upregulation of allograft inflammatory factor-1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype. Int J Mol Med 42:861-872 (2018). PubMed: 29749461
  • Yang M  et al. EphrinB/EphB signaling contributes to spinal nociceptive processing via calpain-1 and caspase-3. Mol Med Rep 18:268-278 (2018). PubMed: 29749521
  • Da Mesquita S  et al. Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease. Nature 560:185-191 (2018). PubMed: 30046111
  • Sanches EF  et al. Brain Metabolism Alterations Induced by Pregnancy Swimming Decreases Neurological Impairments Following Neonatal Hypoxia-Ischemia in Very Immature Rats. Front Neurol 9:480 (2018). PubMed: 29988536
  • Ghumatkar P  et al. The effect of phloretin on synaptic proteins and adult hippocampal neurogenesis in Aß (1-42)-injected male Wistar rats. J Pharm Pharmacol 70:1022-1030 (2018). PubMed: 29682750
  • Lee YC  et al. Manual acupuncture relieves bile acid-induced itch in mice: the role of microglia and TNF-a. Int J Med Sci 15:953-960 (2018). PubMed: 30008609
  • Zheng J  et al. Sirt3 Ameliorates Oxidative Stress and Mitochondrial Dysfunction After Intracerebral Hemorrhage in Diabetic Rats. Front Neurosci 12:414 (2018). PubMed: 29970985
  • Sun Z  et al. Dexmedetomidine attenuates spinal cord ischemia-reperfusion injury through both anti-inflammation and anti-apoptosis mechanisms in rabbits. J Transl Med 16:209 (2018). PubMed: 30031397
  • Sauter MM  et al. Toll-like receptors 4, 5, 6 and 7 are constitutively expressed in non-human primate retinal neurons. J Neuroimmunol 322:26-35 (2018). PubMed: 29954626
  • Garrett L  et al. Analysis of Neuropsychiatric Disease-Related Functional Neuroanatomical Markers in Mice. Curr Protoc Mouse Biol 8:79-128 (2018). PubMed: 30040222
  • Smith NM  et al. Inflammation and blood-brain barrier breach remote from the primary injury following neurotrauma. J Neuroinflammation 15:201 (2018). PubMed: 29981582
  • Gao L  et al. MANF attenuates neuronal apoptosis and promotes behavioral recovery via Akt/MDM-2/p53 pathway after traumatic spinal cord injury in rats. Biofactors N/A:N/A (2018). PubMed: 29797541
  • Remacle N  et al. New in vitro model derived from brain-specific Mut-/- mice confirms cerebral ammonium accumulation in methylmalonic aciduria. Mol Genet Metab 124:266-277 (2018). PubMed: 29934063
  • Wei Y  et al. Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer's disease. Cell Death Dis 9:820 (2018). PubMed: 30050035
  • Smith BM  et al. A Larger Social Network Enhances Novel Object Location Memory and Reduces Hippocampal Microgliosis in Aged Mice. Front Aging Neurosci 10:142 (2018). PubMed: 29904345
  • Zhou YQ  et al. Reactive oxygen species scavengers ameliorate mechanical allodynia in a rat model of cancer-induced bone pain. Redox Biol 14:391-397 (2018). PubMed: 29055283
  • Foditsch EE  et al. A new technique for minimal invasive complete spinal cord injury in minipigs. Acta Neurochir (Wien) 160:459-465 (2018). PubMed: 29330575
  • Kumosa LS  et al. Gelatin promotes rapid restoration of the blood brain barrier after acute brain injury. Acta Biomater 65:137-149 (2018). PubMed: 29037893
  • Chunchai T  et al. Decreased microglial activation through gut-brain axis by prebiotics, probiotics, or synbiotics effectively restored cognitive function in obese-insulin resistant rats. J Neuroinflammation 15:11 (2018). IHC ; Rat . PubMed: 29316965
  • Espino Guarch M  et al. Mutations in L-type amino acid transporter-2 supportSLC7A8as a novel gene involved in age-related hearing loss. Elife 7:N/A (2018). PubMed: 29355479
  • Sokhi UK  et al. Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models. Nat Commun 9:658 (2018). PubMed: 29440643
  • Sumizono M  et al. The effect of exercise frequency on neuropathic pain and pain-related cellular reactions in the spinal cord and midbrain in a rat sciatic nerve injury model. J Pain Res 11:281-291 (2018). PubMed: 29445295
  • Wang JY  et al. Repeated electroacupuncture treatment attenuated hyperalgesia through suppression of spinal glial activation in chronic neuropathic pain rats. BMC Complement Altern Med 18:74 (2018). PubMed: 29466978
  • Sanderson TH  et al. Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury. Sci Rep 8:3481 (2018). PubMed: 29472564
  • Ren HL  et al. Downregulated Nuclear Factor E2-Related Factor 2 (Nrf2) Aggravates Cognitive Impairments via Neuroinflammation and Synaptic Plasticity in the Senescence-Accelerated Mouse Prone 8 (SAMP8) Mouse: A Model of Accelerated Senescence. Med Sci Monit 24:1132-1144 (2018). PubMed: 29474348
  • Zhang F  et al. American Strain of Zika Virus Causes More Severe Microcephaly Than an Old Asian Strain in Neonatal Mice. EBioMedicine 25:95-105 (2017). IHC-P . PubMed: 29107512
  • Krzyzanowska W  et al. Ceftriaxone- and N-acetylcysteine-induced brain tolerance to ischemia: Influence on glutamate levels in focal cerebral ischemia. PLoS One 12:e0186243 (2017). IHC-P . PubMed: 29045497
  • Lipski DA  et al. MHC class II expression and potential antigen-presenting cells in the retina during experimental autoimmune uveitis. J Neuroinflammation 14:136 (2017). IHC-P ; Mouse . PubMed: 28720143
  • Jakovljevic M  et al. Down-regulation of NTPDase2 and ADP-sensitive P2 Purinoceptors Correlate with Severity of Symptoms during Experimental Autoimmune Encephalomyelitis. Front Cell Neurosci 11:333 (2017). PubMed: 29163045
  • Hu Y  et al. Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-?B signaling pathway after LPS treatment in neonatal rats. Oncotarget 8:31638-31654 (2017). PubMed: 28404943
  • Wei CC  et al. Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway. Sci Rep 7:717 (2017). IHC . PubMed: 28386082
  • Wang S  et al. Non-invasive, Focused Ultrasound-Facilitated Gene Delivery for Optogenetics. Sci Rep 7:39955 (2017). PubMed: 28059117
  • Stoney PN  et al. A seasonal switch in histone deacetylase gene expression in the hypothalamus and their capacity to modulate nuclear signaling pathways. Brain Behav Immun 61:340-352 (2017). PubMed: 27993690
  • Ong LK  et al. Early life peripheral lipopolysaccharide challenge reprograms catecholaminergic neurons. Sci Rep 7:40475 (2017). PubMed: 28071709
  • Williams CL  et al. Gene Therapeutic Reversal of Peripheral Olfactory Impairment in Bardet-Biedl Syndrome. Mol Ther 25:904-916 (2017). PubMed: 28237838
  • Sha L  et al. Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy. J Exp Med 214:547-563 (2017). PubMed: 28028152
  • Ashley SL  et al. Matrix Metalloproteinase Activity in Infections by an Encephalitic Virus, Mouse Adenovirus Type 1. J Virol 91:N/A (2017). PubMed: 28053109
  • Lohrke J  et al. Histology and Gadolinium Distribution in the Rodent Brain After the Administration of Cumulative High Doses of Linear and Macrocyclic Gadolinium-Based Contrast Agents. Invest Radiol 52:324-333 (2017). PubMed: 28323657
  • Furukawa T  et al. Chronic diazepam administration increases the expression of Lcn2 in the CNS. Pharmacol Res Perspect 5:e00283 (2017). PubMed: 28596835
  • O'Hare Doig RL  et al. Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma. BMC Neurosci 18:62 (2017). PubMed: 28806920
  • Alidori S  et al. Carbon nanotubes exhibit fibrillar pharmacology in primates. PLoS One 12:e0183902 (2017). PubMed: 28846728
  • Gesteira TF  et al. Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation. Invest Ophthalmol Vis Sci 58:4407-4421 (2017). PubMed: 28863216
  • Song Z  et al. High-fat diet increases pain behaviors in rats with or without obesity. Sci Rep 7:10350 (2017). PubMed: 28871134
  • Krishnan ML  et al. Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants. Nat Commun 8:428 (2017). PubMed: 28874660
  • von Brzezinski L  et al. Low Neurotoxicity of ONX-0914 Supports the Idea of Specific Immunoproteasome Inhibition as a Side-Effect-Limiting, Therapeutic Strategy. Eur J Microbiol Immunol (Bp) 7:234-245 (2017). PubMed: 29034113
  • Mangas A  et al. Gemst: a taylor-made combination that reverts neuroanatomical changes in stroke. Eur J Histochem 61:2790 (2017). PubMed: 28735520
  • Wei X  et al. Impaired Spinal Glucocorticoid Receptor Signaling Contributes to the Attenuating Effect of Depression on Mechanical Allodynia and Thermal Hyperalgesia in Rats with Neuropathic Pain. Front Cell Neurosci 11:145 (2017). PubMed: 28579944
  • Liu PW  et al. P2Y12 and P2Y13 receptors involved in ADPßs induced the release of IL-1ß, IL-6 and TNF-a from cultured dorsal horn microglia. J Pain Res 10:1755-1767 (2017). PubMed: 28794655
  • Burmeister AR  et al. Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P. J Neuroinflammation 14:245 (2017). ICC/IF ; Human . PubMed: 29237453
  • Ferguson SA  et al. Negative Impact of Female Sex on Outcomes from Repetitive Mild Traumatic Brain Injury in hTau Mice Is Age Dependent: A Chronic Effects of Neurotrauma Consortium Study. Front Aging Neurosci 9:416 (2017). PubMed: 29311903
  • Ren LQ  et al. Heterogenic Distribution of Aromatic L-Amino Acid Decarboxylase Neurons in the Rat Spinal Cord. Front Integr Neurosci 11:31 (2017). PubMed: 29225571
  • Li J  et al. Effect of VEGF on Inflammatory Regulation, Neural Survival, and Functional Improvement in Rats following a Complete Spinal Cord Transection. Front Cell Neurosci 11:381 (2017). PubMed: 29238292
  • Andreou KE  et al. Anti-inflammatory Microglia/Macrophages As a Potential Therapeutic Target in Brain Metastasis. Front Oncol 7:251 (2017). PubMed: 29164051
  • Shi L  et al. Hydrogen sulfide ameliorates subarachnoid hemorrhage-induced neuronal apoptosisviathe ROS-MST1 pathway. Oncotarget 8:73547-73558 (2017). PubMed: 29088725
  • Lin MY  et al. Zika Virus Infects Intermediate Progenitor Cells and Post-mitotic Committed Neurons in Human Fetal Brain Tissues. Sci Rep 7:14883 (2017). PubMed: 29093521
  • O'Loughlin E  et al. Acute in utero exposure to lipopolysaccharide induces inflammation in the pre- and postnatal brain and alters the glial cytoarchitecture in the developing amygdala. J Neuroinflammation 14:212 (2017). PubMed: 29096641
  • Fang M  et al. Metformin treatment after the hypoxia-ischemia attenuates brain injury in newborn rats. Oncotarget 8:75308-75325 (2017). PubMed: 29088867
  • Aoyagi-Scharber M  et al. Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice. Mol Ther Methods Clin Dev 6:43-53 (2017). IHC-P ; Mouse . PubMed: 28664165
  • Wang XH  et al. Inhibiting purinergic P2X7 receptors with the antagonist brilliant blue G is neuroprotective in an intranigral lipopolysaccharide animal model of Parkinson's disease. Mol Med Rep 15:768-776 (2017). IHC . PubMed: 28035410
  • Guo X  et al. Amyloid ß-Induced Redistribution of Transcriptional Factor EB and Lysosomal Dysfunction in Primary Microglial Cells. Front Aging Neurosci 9:228 (2017). PubMed: 28769785
  • Hu XM  et al. Chemokine receptor CXCR4 regulates CaMKII/CREB pathway in spinal neurons that underlies cancer-induced bone pain. Sci Rep 7:4005 (2017). PubMed: 28638088
  • Cheng L  et al. Identification of spinal circuits involved in touch-evoked dynamic mechanical pain. Nat Neurosci 20:804-814 (2017). IHC ; Mouse . PubMed: 28436981
  • Shi Y  et al. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth. Nat Commun 8:15080 (2017). ICC/IF ; Human . PubMed: 28569747
  • Mardiguian S  et al. The contribution of the acute phase response to the pathogenesis of relapse in chronic-relapsing experimental autoimmune encephalitis models of multiple sclerosis. J Neuroinflammation 14:196 (2017). IHC ; Rat . PubMed: 28964257
  • Zukor K  et al. Phrenic nerve deficits and neurological immunopathology associated with acute West Nile virus infection in mice and hamsters. J Neurovirol 23:186-204 (2017). PubMed: 27761801
  • Casanovas A  et al. Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury. Sci Rep 7:40155 (2017). PubMed: 28065942
  • Li DJ  et al. The novel exercise-induced hormone irisin protects against neuronal injury via activation of the Akt and ERK1/2 signaling pathways and contributes to the neuroprotection of physical exercise in cerebral ischemia. Metabolism 68:31-42 (2017). PubMed: 28183451
  • Abu El-Asrar AM  et al. Osteoprotegerin Is a New Regulator of Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy. Invest Ophthalmol Vis Sci 58:3189-3201 (2017). PubMed: 28654984
  • Hodges JL  et al. Astrocytic Contributions to Synaptic and Learning Abnormalities in a Mouse Model of Fragile X Syndrome. Biol Psychiatry 82:139-149 (2017). PubMed: 27865451
  • Abud EM  et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron 94:278-293.e9 (2017). PubMed: 28426964
  • Chandra G  et al. Induction of Adaptive Immunity Leads to Nigrostriatal Disease Progression in MPTP Mouse Model of Parkinson's Disease. J Immunol 198:4312-4326 (2017). PubMed: 28446566
  • Bohlen CJ  et al. Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures. Neuron 94:759-773.e8 (2017). PubMed: 28521131
  • Manso Y  et al. Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease. Glia N/A:N/A (2017). PubMed: 28722234
  • Semple BD  et al. Interleukin-1 Receptor in Seizure Susceptibility after Traumatic Injury to the Pediatric Brain. J Neurosci 37:7864-7877 (2017). PubMed: 28724747
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