Overview

  • Product name

    Iberin, natural isothiocyanate
  • Description

    A natural isothiocyanate
  • Biological description

    A natural isothiocyanate. Induces expression of phase II detoxification enzymes, including quinone reductase and glutathione S-transferase. Inhibits expression of Cdk2, Cdk4, and Cdk6 proteins in vivo, inducing cell-cycle arrest and apoptosis.
  • Purity

    > 97%
  • CAS Number

    505-44-2
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Jakobsen TH  et al. Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol 78:2410-21 (2012). Read more (PubMed: 22286987) »
  • Jadhav U  et al. Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells. Int J Mol Med 19:353-61 (2007). Read more (PubMed: 17273780) »
  • Munday R & Munday CM Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J Agric Food Chem 52:1867-71 (2004). Read more (PubMed: 15053522) »

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