Ibuprofen lysine, Non-selective COX-inhibitor NSAID (ab145655)

Overview

  • Product name

    Ibuprofen lysine, Non-selective COX-inhibitor NSAID
  • Description

    Non-steroidal anti-inflammatory drug. Non-selective COX-inhibitor.
  • Alternative names

    • NeoProfen
    • Nurofen
  • Biological description

    Non-steroidal anti-inflammatory drug. Non-selective Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

  • Purity

    > 99%
  • CAS Number

    57469-77-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Lysine 2-(p-isobutylphenyl)propionate
  • Molecular weight

    352.47
  • Molecular formula

    C19H32N2O4
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Matos P & Jordan P Beyond COX-inhibition: 'side-effects' of ibuprofen on neoplastic development and progression. Curr Pharm Des 21:2978-82 (2015). Read more (PubMed: 26004413) »
  • Capparelli EV Pharmacologic, pharmacodynamic, and pharmacokinetic considerations with intravenous Ibuprofen lysine. J Pediatr Pharmacol Ther 12:158-70 (2007). Read more (PubMed: 23055851) »
  • Kato M  et al. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes. J Pharm Pharmacol 53:1679-85 (2001). Read more (PubMed: 11804398) »

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