Overview

  • Product name

    Ibuprofen, NSAID
  • Description

    A nonsteroidal anti-inflammatory drug (NSAID). COX inhibitor.
  • Biological description

    A nonsteroidal anti-inflammatory drug (NSAID). Non-selective inhibitor of COX-1 and COX-2 (IC50 values are 12 and 80 µM respectively). Inhibits thromboxane B2 release (IC50 = 1.27 µM) and anandamide metabolism (IC50 = 400 µM).
  • Purity

    > 99%
  • CAS Number

    15687-27-1
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Kato M  et al. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes. J Pharm Pharmacol 53:1679-85 (2001). Read more (PubMed: 11804398) »
  • Díaz AM  et al. In vitro anti-inflammatory activity of iridoids and triterpenoid compounds isolated from Phillyrea latifolia L. Biol Pharm Bull 23:1307-13 (2000). Read more (PubMed: 11085357) »
  • Fowler CJ  et al. Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide. Pharmacol Toxicol 80:103-7 (1997). Read more (PubMed: 9060042) »

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