Overview

  • Product name

  • Description

    Rabbit polyclonal to ICA69
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Xenopus laevis, Xenopus tropicalis
  • Immunogen

    Recombinant fragment corresponding to Human ICA69 aa 1-223.
    Database link: Q05084

  • Positive control

    • A549 whole cell lysate; Human A2780-CP70 xenograft tissue.
  • General notes

    Previously labelled as ICA1. 

Properties

Applications

Our Abpromise guarantee covers the use of ab154391 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 55 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    May play a role in neurotransmitter secretion.
  • Tissue specificity

    Expressed abundantly in pancreas, heart and brain with low levels of expression in lung, kidney, liver and thyroid.
  • Sequence similarities

    Contains 1 AH domain.
  • Cellular localization

    Cytoplasm > cytosol. Golgi apparatus membrane. Cytoplasmic vesicle > secretory vesicle membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
  • Information by UniProt
  • Database links

  • Alternative names

    • 69 kDa islet cell autoantigen antibody
    • Diabetes mellitus type I autoantigen antibody
    • ICA 1 antibody
    • Ica1 antibody
    • ICA69 antibody
    • ICA69_HUMAN antibody
    • ICAp69 antibody
    • Islet cell autoantigen 1 (69kD) antibody
    • Islet cell autoantigen 1 69kDa antibody
    • Islet cell autoantigen 1 antibody
    • Islet cell autoantigen 1 isoform antibody
    • Islet cell autoantigen p69 antibody
    • OTTHUMP00000200933 antibody
    • OTTHUMP00000200934 antibody
    • OTTHUMP00000200941 antibody
    • OTTHUMP00000200993 antibody
    • p69 antibody
    see all

Images

  • Anti-ICA69 antibody (ab154391) at 1/1000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size: 55 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human A2780-CP70 xenograft tissue labeling ICA69 with ab154391 at 1/100 dilution.

References

ab154391 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab154391.
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