Name: Anti-ICAD antibody
SKU: ab2040

Product name

Anti-ICAD antibody
See all ICAD primary antibodies
Description

Rabbit polyclonal to ICAD
Host species

Rabbit
Tested applications

Suitable for: IHC-FrFl, WBmore details
Species reactivity

Reacts with: Mouse
Immunogen

Synthetic peptide, corresponding to amino acids 312-331 of Mouse ICAD (CT).
Positive control
- Mouse lung tissue lysate.
General notes

Stable for one year.

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C.
Storage buffer

Preservative: 0.02% Sodium azide
Constituent: PBS
Concentration information loading...
Purity

Immunogen affinity purified
Clonality

Polyclonal
Isotype

IgG
Research areas
- Cell Biology
- Apoptosis
- Nucleus
- DNAses
- Cancer
- Cell Death
- Apoptosis
- Nucleus
- DNAses

Compatible Secondaries
- Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
- Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
Immunizing Peptide (Blocking)
- ICAD peptide (ab6103)
Isotype control
- Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

Our Abpromise guarantee covers the use of ab2040 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application	Abreviews	Notes
IHC-FrFl		Use a concentration of 5 µg/ml.
WB		1/500 - 1/2000. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).Can be blocked with ICAD peptide (ab6103).

Function

Inhibitor of the caspase-activated DNase (DFF40).
Sequence similarities

Contains 1 CIDE-N domain.
Post-translational
modifications

Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localization

Cytoplasm.
Target information above from: UniProt accession O00273 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 13347 Mouse
- SwissProt: O54786 Mouse
- Unigene: 41433 Mouse
Alternative names
- A330085O09Rik antibody
- Caspase activated deoxyribonuclease inhibitor short form antibody
- DFF 1 antibody
- DFF 45 antibody
- DFF alpha antibody
- DFF-45 antibody
- DFF1 antibody
- DFF35 antibody
- DFF45 antibody
- DFFA antibody
- Dffa DNA fragmentation factor, alpha subunit antibody
- DFFA_HUMAN antibody
- DNA fragmentation factor 45 kDa subunit antibody
- DNA Fragmentation Factor Alpha Subunit antibody
- DNA fragmentation factor subunit alpha antibody
- DNA fragmentation factor, 45 kD, alpha subunit antibody
- DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1 antibody
- DNA fragmentation factor, 45kDa, alpha polypeptide antibody
- DNA fragmentation factor, alpha subunit antibody
- DNAation factor 45 kDa subunit antibody
- H13 antibody
- ICAD antibody
- ICAD L antibody
- ICAD S antibody
- Inhibitor of CAD antibody
- Inhibitor of Caspase Activated DNase antibody
- MGC143066 antibody
- OTTHUMP00000001903 antibody
- OTTHUMP00000001904 antibody
- RP23 121D17.3 antibody
see all

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ICAD antibody (ab2040)

Immunohistochemistry (Formalin-fixed paraffin embedded sections) of mouse kidney tissue labeling ICAD with Anti-ICAD antibody (ab2040) at 5μg/ml.
Western blot - Anti-ICAD antibody (ab2040)

Western blot analysis of ICAD in murine lung (L), brain (B), liver (L), and kidney tissue lysate with anti-ICAD (CT) at 1/1000 dilution.

Western blot protocols

Datasheet

ab2040 has not yet been referenced specifically in any publications.

Publishing research using ab2040? Please let us know so that we can cite the reference in this datasheet.

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Anti-ICAD antibody (ab2040)

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