Anti-ICAD antibody (ab2040)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-ICAD antibody
See all ICAD primary antibodies -
DescriptionRabbit polyclonal to ICAD
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Host speciesRabbit
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Tested applicationsSuitable for: IHC-FrFl, WBmore details
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Species reactivityReacts with: Mouse
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Immunogen
Synthetic peptide, corresponding to amino acids 312-331 of Mouse ICAD (CT).
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Positive control
- Mouse lung tissue lysate.
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General notesStable for one year.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C.
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Storage bufferPreservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Immunizing Peptide (Blocking)
Applications
Our Abpromise guarantee covers the use of ab2040 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-FrFl | Use a concentration of 5 µg/ml. | |
| WB | 1/500 - 1/2000. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).Can be blocked with ICAD peptide (ab6103). |
Target
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FunctionInhibitor of the caspase-activated DNase (DFF40).
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Sequence similaritiesContains 1 CIDE-N domain.
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Post-translational
modificationsCaspase-3 cleaves DFF45 at 2 sites to generate an active factor.
Phosphorylated upon DNA damage, probably by ATM or ATR. -
Cellular localizationCytoplasm.
- Information by UniProt
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Database links
- Entrez Gene: 13347 Mouse
- SwissProt: O54786 Mouse
- Unigene: 41433 Mouse
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Alternative names
- A330085O09Rik antibody
- Caspase activated deoxyribonuclease inhibitor short form antibody
- DFF 1 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ICAD antibody (ab2040)Immunohistochemistry (Formalin-fixed paraffin embedded sections) of mouse kidney tissue labeling ICAD with Anti-ICAD antibody (ab2040) at 5μg/ml. -
Western blot - Anti-ICAD antibody (ab2040)Western blot analysis of ICAD in murine lung (L), brain (B), liver (L), and kidney tissue lysate with anti-ICAD (CT) at 1/1000 dilution.
Datasheets and documents
Protocols
References
ab2040 has not yet been referenced specifically in any publications.
