• Product name

    Anti-ICAD antibody [EPR4222(2)]
    See all ICAD primary antibodies
  • Description

    Rabbit monoclonal [EPR4222(2)] to ICAD
  • Host species

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human ICAD aa 200-300. The exact sequence is proprietary.

  • Positive control

    • HepG2, U937, A431, and A549 cell lysates
  • General notes



    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab108521 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Predicted molecular weight: 37 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function

      Inhibitor of the caspase-activated DNase (DFF40).
    • Sequence similarities

      Contains 1 CIDE-N domain.
    • Post-translational

      Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization

    • Information by UniProt
    • Database links

    • Alternative names

      • A330085O09Rik antibody
      • Caspase activated deoxyribonuclease inhibitor short form antibody
      • DFF 1 antibody
      • DFF 45 antibody
      • DFF alpha antibody
      • DFF-45 antibody
      • DFF1 antibody
      • DFF35 antibody
      • DFF45 antibody
      • DFFA antibody
      • Dffa DNA fragmentation factor, alpha subunit antibody
      • DFFA_HUMAN antibody
      • DNA fragmentation factor 45 kDa subunit antibody
      • DNA Fragmentation Factor Alpha Subunit antibody
      • DNA fragmentation factor subunit alpha antibody
      • DNA fragmentation factor, 45 kD, alpha subunit antibody
      • DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1 antibody
      • DNA fragmentation factor, 45kDa, alpha polypeptide antibody
      • DNA fragmentation factor, alpha subunit antibody
      • DNAation factor 45 kDa subunit antibody
      • H13 antibody
      • ICAD antibody
      • ICAD L antibody
      • ICAD S antibody
      • Inhibitor of CAD antibody
      • Inhibitor of Caspase Activated DNase antibody
      • MGC143066 antibody
      • OTTHUMP00000001903 antibody
      • OTTHUMP00000001904 antibody
      • RP23 121D17.3 antibody
      see all


    • All lanes : Anti-ICAD antibody [EPR4222(2)] (ab108521) at 1/10000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : U937 cell lysate
      Lane 3 : A431 cell lysate
      Lane 4 : A549 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 37 kDa


    This product has been referenced in:

    • Wang FZ  et al. Molecular mechanisms underlying the a-tomatine-directed apoptosis in human malignant glioblastoma cell lines A172 and U-118 MG. Exp Ther Med 14:6183-6192 (2017). Read more (PubMed: 29250143) »
    See 1 Publication for this product

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