Overview

  • Product name

    Icilin, TRPM8 agonist
  • Description

    TRPM8 agonist. Super-cooling agent.
  • Biological description

    TRPM8 agonist (EC50 values are 0.4 and 7 μM in the presence and absence of Ca2+ respectively). Super-cooling agent. Weakly activates TRPA1. Inhibits TRPV3 (IC50 values are 0.5 and 7 μM in the presence and absence of Ca2+ respectively). Produces wet-dog shakes in vivo.
  • Purity

    > 97%
  • CAS Number

    36945-98-9
  • Chemical structure

    Chemical Structure

Properties

References

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