Overview

  • Product name

    iCRT5, CRT Inhibitor, CRT inhibitor
  • Description

    Cell-permeable CRT inhibitor
  • Biological description

    Cell-permeable β-catenin-responsive transcription (CRT) inhibitor. Wnt responsive STF16 luciferase inhibitor (IC50 = 18 nM). Active in vitro.
  • Purity

    > 98%
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Anastas JN & Moon RT WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer 13:11-26 (2013). Read more (PubMed: 23258168) »
  • Gonsalves FC  et al. An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway. Proc Natl Acad Sci U S A 108:5954-63 (2011). Read more (PubMed: 21393571) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab142141.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up